SCHEMBL13640167

SCHEMBL13640167

CC1(C)CC(=O)C(=CNc2ccc(F)c(Cl)c2)C(=O)C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.54
▸ MEN1 O00255 5/20 0.54
▸ POLB P06746 1/20 0.47
▸ BUB1 O43683 1/20 0.46
▸ CYP11B2 P19099 1/20 0.44
▸ ALDH1A1 P00352 5/20 0.40
▸ NPC1 O15118 3/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ LMNA P02545 2/20 0.40
▸ ALOX15 P16050 2/20 0.40
▸ TSHR P16473 2/20 0.40
▸ HTT P42858 3/20 0.39
▸ SLC2A1 P11166 1/20 0.38
▸ MAPT P10636 3/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ GLA P06280 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13640151 0.87 BUB1 (0.43) KMT2AMEN1BUB1CYP11B2ALDH1A1
SCHEMBL18871421 0.85 BUB1 (0.45) KMT2AMEN1BUB1CYP11B2ALDH1A1
SCHEMBL13640140 0.85 PKM (0.46) KMT2AMEN1BUB1ALDH1A1NPC1
SCHEMBL22057718 0.83 MAOA (0.45) KMT2AMEN1POLBBUB1CYP11B2
SCHEMBL18871529 0.83 ALDH1A1 (0.39) KMT2AMEN1BUB1CYP11B2ALDH1A1
SCHEMBL18870996 0.83 KMT2A (0.36) KMT2AMEN1BUB1CYP11B2ALDH1A1
SCHEMBL13640458 0.81 MEN1 (0.46) KMT2AMEN1BUB1CYP11B2ALDH1A1
SCHEMBL13640157 0.80 CYP11B2 (0.40) KMT2AMEN1BUB1CYP11B2ALDH1A1
SCHEMBL13640141 0.80 ALDH1A1 (0.60) KMT2AMEN1BUB1CYP11B2ALDH1A1
SCHEMBL18871104 0.77 BUB1 (0.41) KMT2AMEN1BUB1ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013163454-A2 PSYLLID ATTRACTANTS AND THEIR USES INSCENT, INC. (US) 2013-10-31 — — WO claimed
EP-2477491-B1 PLANT ADDITIVES AND USES THEREOF TO MODULATE THE SYNTHESIS OF MEMBRANE GLYCEROLIPIDS IN PLANTS COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-05-17 — — EP disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-9028855-B2 Plant additives and uses thereof to modulate the synthesis of membrane glycerolipids in planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-12 — — US disclosed
US-20130287727-A1 Psyllid Attractants and Their Uses INSCENT, INC. (US) 2013-10-31 — — US disclosed
WO-2013163454-A2 PSYLLID ATTRACTANTS AND THEIR USES INSCENT, INC. (US) 2013-10-31 — — WO disclosed
US-20130287727-A1 Psyllid Attractants and Their Uses INSCENT, INC. (US) 2013-10-31 — — US disclosed
US-20130287727-A1 Psyllid Attractants and Their Uses INSCENT, INC. (US) 2013-10-31 — — US disclosed
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-11-08 — — US disclosed
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2012-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130287727-A1 Psyllid Attractants and Their Uses L3MBTL3, LPAR3, LPXN KMT2A 1612/4885MEN1 4287/4885POLB 3313/4885
US-20120283101-A1 Plant Additives and Uses Thereof to Modulate the Synthesis of Membrane Glycerolipids in Planta PGM2, SGMS2, PHOSPHO1 KMT2A 1828/4885MEN1 2145/4885POLB 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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