Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | IDE | P14735 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028112 | 0.82 | CA2 (0.57) | LMNACA1CA2MAPTALDH1A1 | |
| SCHEMBL11329269 | 0.82 | HSD17B10 (0.55) | LMNASERPINE1CA1CA2MAPT | |
| SCHEMBL28202113 | 0.81 | TDP1 (0.44) | LMNASMN1; SMN2MAPTALDH1A1GAA | |
| SCHEMBL27903840 | 0.78 | PTGS2 (0.40) | ENPP2LMNAG6PDIDESMN1; SMN2 | |
| SCHEMBL5020928 | 0.77 | SERPINE1 (0.61) | ENPP2LMNASERPINE1CA1CA2 | |
| SCHEMBL14146435 | 0.77 | PTGS2 (0.43) | G6PDIDESMN1; SMN2 | |
| SCHEMBL28211358 | 0.77 | LMNA (0.51) | LMNAG6PDIDESMN1; SMN2MAPT | |
| SCHEMBL19266099 | 0.77 | LMNA (0.56) | ENPP2LMNAAKR1C3MAPTALDH1A1 | |
| SCHEMBL647314 | 0.76 | FTO (0.59) | CA1CA2MAPTGAACDK1 | |
| SCHEMBL647313 | 0.76 | FTO (0.59) | CA1CA2MAPTGAACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246211-A1 | Molecular constructs suitable for targeted conjugates | TAPESTRY PHARMACEUTICALS, INC. | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246211-A1 | Molecular constructs suitable for targeted conjugates | MRPL21, QSOX1, MLX | ENPP2 1912/4885LMNA 1851/4885SERPINE1 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.