Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.75 |
| ▸ | MLNR | O43193 | 1/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.73 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.73 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | DRD1 | P21728 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | HRH2 | P25021 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.73 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14597388 | 1.00 | BLM (0.75) | BLMMLNRNR1I2PGRADRB1 | |
| Bromide SCHEMBL31621175 | 0.99 | BLM (0.74) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL17445527 | 0.99 | BLM (0.76) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL16692020 | 0.97 | PRMT1 (0.72) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL19130572 | 0.97 | PRMT1 (0.72) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL19632961 | 0.96 | BLM (0.72) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL24968124 | 0.96 | BLM (0.69) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL24968104 | 0.95 | PRMT1 (0.69) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL249681 | 0.95 | MLNR (0.83) | BLMMLNRNR1I2PGRADRB1 | |
| SCHEMBL20042445 | 0.95 | MLNR (0.83) | BLMMLNRNR1I2PGRADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9844606-B2 | Indocyanine compound, synthesis method and purification method thereof, diagnostic composition using the indocyanine compound, and device for measuring biokinetics and device for visualizing circulation using the diagnostic composition | NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY (JP) | 2017-12-19 | — | — | US | disclosed |
| US-20170157273-A1 | NOVEL INDOCYANINE COMPOUND, SYNTHESIS METHOD AND PURIFICATION METHOD THEREOF, DIAGNOSTIC COMPOSITION USING THE INDOCYANINE COMPOUND, AND DEVICE FOR MEASURING BIOKINETICS AND DEVICE FOR VISUALIZING CIRCULATION USING THE DIAGNOSTIC COMPOSITION | NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY (JP) | 2017-06-08 | — | — | US | disclosed |
| US-9283288-B2 | Methods of using optical agents | MEDIBEACON, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20160067359-A1 | COMPOSITION HAVING DYE AND CONJUGATE OF POLYETHYLENEGLYCOL AND ADDITIVE AND CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2016-03-10 | — | — | US | disclosed |
| US-20150152267-A1 | NOVEL INDOCYANINE COMPOUND, SYNTHESIS METHOD AND PURIFICATION METHOD THEREOF, DIAGNOSTIC COMPOSITION USING THE INDOCYANINE COMPOUND, AND DEVICE FOR MEASURING BIOKINETICS AND DEVICE FOR VISUALIZING CIRCULATION USING THE DIAGNOSTIC COMPOSITION | NATIONAL UNIVERSITY CORPORATION MIE UNIVERSITY (JP) | 2015-06-04 | — | — | US | disclosed |
| US-7608244-B2 | Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients | MALLINCKRODT INC. (US) | 2009-10-27 | — | — | US | disclosed |
| US-20090263327-A1 | MINIMALLY INVASIVE PHYSIOLOGICAL FUNCTION MONITORING AGENTS | MALLINCKRODT INC. (US) | 2009-10-22 | — | — | US | disclosed |
| US-7556797-B2 | Minimally invasive physiological function monitoring agents | MALLINCKRODT INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7468177-B2 | Hydrophilic light absorbing compositions for determination of physiological function in critically ill patients | MALLINCKRODT INC. (US) | 2008-12-23 | — | — | US | disclosed |
| US-20080312539-A1 | Methods of Using Optical Agents | MEDIBEACON, INC. | 2008-12-18 | — | — | US | disclosed |
| US-7438894-B2 | Dyes for organ function monitoring | MALLINCKRODT, INC. (US) | 2008-10-21 | — | — | US | disclosed |
| US-20080056989-A1 | Novel Dyes for Organ Function Monitoring | MALLINCKRODT, INC. (US) | 2008-03-06 | — | — | US | disclosed |
| US-20070269373-A1 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | MALLINCKRODT, INC. (US) | 2007-11-22 | — | — | US | disclosed |
| US-20070269368-A1 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | MALLINCKRODT, INC. (US) | 2007-11-22 | — | — | US | disclosed |
| US-7297325-B2 | Hydrophilic light absorbing compositions for determination of physiological function | MALLINCKRODT INC. (US) | 2007-11-20 | — | — | US | disclosed |
| US-20070140962-A1 | Light Sensitive Compounds for Instant Determination of Organ Function | MALLINCKRODT INC. (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070092450-A1 | TISSUE-SPECIFIC EXOGENOUS OPTICAL AGENTS | MALLINCKRODT INC. (US) | 2007-04-26 | — | — | US | disclosed |
| US-7175831-B2 | Light sensitive compounds for instant determination of organ function | MALLINCKRODT, INC. (US) | 2007-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080056989-A1 | Novel Dyes for Organ Function Monitoring | TNNI3, TNNT2, TPH1 | BLM 3105/4885MLNR 511/4885NR1I2 767/4885 |
| US-20160067359-A1 | COMPOSITION HAVING DYE AND CONJUGATE OF POLYETHYLENEGLYCOL AND ADDITIVE AND CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING HAVING THE SAME | ALG1, PHOSPHO1, COL1A1 | BLM 2310/4885MLNR 1078/4885NR1I2 1147/4885 |
| US-20070140962-A1 | Light Sensitive Compounds for Instant Determination of Organ Function | TNNI3, TNNC1, TNNT2 | BLM 3544/4885MLNR 682/4885NR1I2 1210/4885 |
| US-20070269368-A1 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | TNNI3, IDO1, TPH1 | BLM 2177/4885MLNR 1026/4885NR1I2 799/4885 |
| US-20150152267-A1 | NOVEL INDOCYANINE COMPOUND, SYNTHESIS METHOD AND PURIFICATION METHOD THEREOF, DIAGNOSTIC COMPOSITION USING THE INDOCYANINE COMPOUND, AND DEVICE FOR MEASURING BIOKINETICS AND DEVICE FOR VISUALIZING CIRCULATION USING THE DIAGNOSTIC COMPOSITION | GYS2, PYGL, GPR119 | BLM 1854/4885MLNR 2432/4885NR1I2 991/4885 |
| US-20170157273-A1 | NOVEL INDOCYANINE COMPOUND, SYNTHESIS METHOD AND PURIFICATION METHOD THEREOF, DIAGNOSTIC COMPOSITION USING THE INDOCYANINE COMPOUND, AND DEVICE FOR MEASURING BIOKINETICS AND DEVICE FOR VISUALIZING CIRCULATION USING THE DIAGNOSTIC COMPOSITION | GYS2, PYGL, GPR119 | BLM 1854/4885MLNR 2432/4885NR1I2 991/4885 |
| US-20070269373-A1 | HYDROPHILIC LIGHT ABSORBING COMPOSITIONS FOR DETERMINATION OF PHYSIOLOGICAL FUNCTION IN CRITICALLY ILL PATIENTS | TNNI3, IDO1, TPH1 | BLM 2177/4885MLNR 1026/4885NR1I2 799/4885 |
| US-20090263327-A1 | MINIMALLY INVASIVE PHYSIOLOGICAL FUNCTION MONITORING AGENTS | TNNI3, MB, TNNT2 | BLM 2041/4885MLNR 535/4885NR1I2 1269/4885 |
| US-20070092450-A1 | TISSUE-SPECIFIC EXOGENOUS OPTICAL AGENTS | TNNI3, TNNT2, TNNC1 | BLM 2919/4885MLNR 1269/4885NR1I2 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.