SCHEMBL1367377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8492044	0.83	ALDH1A1 (0.47)	PLA2G7ALDH1A1CASP3SENP8SENP7
	SCHEMBL3830934	0.81	PLA2G7 (0.55)	PLA2G7ALDH1A1RORBCASP3SENP8
	SCHEMBL27623752	0.80	RECQL (0.47)	ALDH1A1MAPTTAS1R3TAS1R1TAS1R2
	SCHEMBL3835536	0.79	CYP1A2 (0.61)	PLA2G7ALDH1A1RORBCASP3SENP8
	SCHEMBL3830939	0.78	MAPT (0.57)	PLA2G7ALDH1A1CASP3SENP8SENP7
	SCHEMBL29752158	0.75	PLA2G7 (0.56)	PLA2G7ALDH1A1CASP3SENP8SENP7
	SCHEMBL11708241	0.74	PLA2G7 (0.55)	PLA2G7ALDH1A1CASP3SENP8SENP7
	SCHEMBL175249	0.74	ALDH1A1 (0.67)	PLA2G7ALDH1A1CASP3SENP8SENP7
	SCHEMBL2008703	0.74	PLA2G7 (0.57)	PLA2G7ALDH1A1CASP3SENP8SENP7
	SCHEMBL8772481	0.73	PLA2G7 (0.53)	PLA2G7ALDH1A1RBBP9CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.