Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | PEPD | P12955 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680461 | 0.85 | SMN1; SMN2 (0.60) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL13680705 | 0.83 | ALDH1A1 (0.48) | KIF11ALDH1A1NPC1GAAMAPT | |
| SCHEMBL13680510 | 0.82 | ALDH1A1 (0.52) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL13680486 | 0.82 | MAPT (0.52) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL13680492 | 0.81 | TSHR (0.51) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL3896317 | 0.79 | ALDH1A1 (0.60) | KIF11ALDH1A1NPC1GAAMAPT | |
| SCHEMBL13680503 | 0.77 | GSK3B (0.62) | ALDH1A1NPC1GAAKDM4EHPGD | |
| SCHEMBL13680490 | 0.77 | PSMB8 (0.54) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL23197679 | 0.75 | TDP1 (0.56) | ALDH1A1NPC1GAAMAPTMEN1 | |
| SCHEMBL5428805 | 0.74 | KIF11 (1.00) | KIF11ALDH1A1NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |