Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738654 | 0.83 | RAB9A (0.73) | RAB9AKMT2AALDH1A1PKMABHD6 | |
| SCHEMBL13680438 | 0.82 | LMNA (0.67) | HSD17B2HSD17B1KMT2AMAOBPPARG | |
| M-Tolyl Dimethylcarbamate SCHEMBL8926857 | 0.82 | LMNA (0.65) | RAB9AKMT2AMAOBACHELMNA | |
| SCHEMBL13680495 | 0.81 | MEN1 (0.52) | HSD17B2HSD17B1KMT2APPARGPPARA | |
| SCHEMBL9257348 | 0.79 | ACHE (0.59) | RAB9AKMT2AALDH1A1PKMACHE | |
| SCHEMBL13680464 | 0.78 | ALDH1A1 (0.48) | RAB9AKMT2AALDH1A1PPARGPPARA | |
| P-Tolyl Dimethylcarbamate SCHEMBL360147 | 0.77 | RAB9A (0.83) | RAB9AKMT2AALDH1A1PKMACHE | |
| SCHEMBL6450091 | 0.77 | RAB9A (1.00) | RAB9AKMT2AALDH1A1PKMACHE | |
| SCHEMBL13680496 | 0.76 | HSD17B2 (0.72) | HSD17B2HSD17B1ALDH1A1LMNATSHR | |
| SCHEMBL13680799 | 0.76 | ACHE (0.52) | RAB9AKMT2AALDH1A1PKMABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |