Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680648 | 0.85 | HSD17B10 (0.51) | EGLN1WNT3ACNR1MAP4K4AAK1 | |
| SCHEMBL22070487 | 0.79 | CYP4F2 (0.66) | ALDH1A1EGLN1CYP4F2CYP4A11WNT3A | |
| SCHEMBL13680515 | 0.78 | FAAH (0.66) | FAAHALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL8241210 | 0.77 | HPGD (0.46) | FAAHALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL13680466 | 0.77 | FAAH (0.56) | FAAHALDH1A1CYP3A4MAPK1HPGD | |
| SCHEMBL13680647 | 0.76 | MAP4K4 (0.67) | HPGDEGLN1MAP4K4 | |
| SCHEMBL13680686 | 0.75 | CYP2A6 (0.45) | AAK1 | |
| SCHEMBL13680499 | 0.73 | MAPK1 (0.51) | ALDH1A1MAPK1EGLN1CYP4F2CYP4A11 | |
| SCHEMBL13680653 | 0.73 | KMO (0.48) | ALDH1A1EGLN1CYP4F2CYP4A11MAP4K4 | |
| SCHEMBL13525194 | 0.73 | CHRM3 (0.60) | FAAHALDH1A1CYP3A4MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |