Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680490 | 0.85 | PSMB8 (0.54) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13680461 | 0.83 | SMN1; SMN2 (0.60) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13680488 | 0.82 | KIF11 (0.59) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13680510 | 0.81 | ALDH1A1 (0.52) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13680492 | 0.79 | TSHR (0.51) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7251623 | 0.78 | SMN1; SMN2 (0.72) | MAPTALDH1A1HPGDNPC1GAA | |
| SCHEMBL13680716 | 0.77 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5655892 | 0.77 | GSK3B (0.64) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9609808 | 0.76 | SMN1; SMN2 (0.82) | MAPTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL13680705 | 0.75 | ALDH1A1 (0.48) | MAPTMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |