Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680796 | 0.86 | AOC3 (0.56) | AOC3FFAR1MAPT | |
| SCHEMBL13680803 | 0.84 | CNR1 (0.44) | AOC3FFAR1CNR1CSF1RFLT1 | |
| SCHEMBL13680802 | 0.84 | MGLL (0.45) | AOC3FFAR1MAPTGPR52 | |
| SCHEMBL13680807 | 0.83 | AOC3 (0.61) | AOC3 | |
| SCHEMBL13680794 | 0.82 | AOC3 (0.53) | AOC3GPR52PDE4D | |
| SCHEMBL13680792 | 0.78 | MEN1 (0.42) | KIF11AOC3FFAR1FFAR4GAA | |
| SCHEMBL8413593 | 0.78 | TAAR1 (0.44) | GPR52 | |
| SCHEMBL418611 | 0.77 | GPR52 (0.50) | AOC3FFAR1FFAR4GPR52 | |
| SCHEMBL13681324 | 0.77 | BCL2 (0.63) | AOC3GPR52 | |
| SCHEMBL13680788 | 0.76 | MAPT (0.50) | AOC3MAPTGPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |