Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680796 | 0.87 | AOC3 (0.56) | SMN1; SMN2AOC3HPGDMAPTFFAR1 | |
| SCHEMBL13680803 | 0.85 | CNR1 (0.44) | MGLLAOC3FFAR1 | |
| SCHEMBL13680800 | 0.84 | KIF11 (0.52) | AOC3MAPTGPR52FFAR1 | |
| SCHEMBL13680807 | 0.84 | AOC3 (0.61) | AOC3 | |
| SCHEMBL13680789 | 0.82 | ERN1 (0.50) | RAB9AMAPTPLAU | |
| SCHEMBL13680793 | 0.79 | BCHE (0.47) | SMN1; SMN2NPC1RAB9AHPGDMAPT | |
| SCHEMBL13680784 | 0.78 | ABL1 (0.50) | SMN1; SMN2HPGDGPR52FFAR1 | |
| SCHEMBL13680788 | 0.77 | MAPT (0.50) | SMN1; SMN2AOC3MAPTGPR52 | |
| SCHEMBL13680804 | 0.76 | HSD17B1 (0.47) | SMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL13680791 | 0.76 | GAA (0.55) | SMN1; SMN2NPC1RAB9AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |