Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680806 | 0.85 | CYP4F2 (0.50) | HIF1ACYP4F2CYP4A11 | |
| SCHEMBL31215931 | 0.81 | BCL2 (0.61) | HIF1ACYP4F2CYP4A11P4HTMBCL2 | |
| SCHEMBL13680797 | 0.80 | CYP11B2 (0.38) | HIF1ACYP4F2CYP4A11 | |
| SCHEMBL13680808 | 0.80 | EPHX2 (0.38) | HIF1ACYP4F2CYP4A11TSHR | |
| SCHEMBL13681324 | 0.79 | BCL2 (0.63) | ACMSDBCL2GPR52 | |
| SCHEMBL418611 | 0.76 | GPR52 (0.50) | ACMSDBCL2GPR52 | |
| SCHEMBL13680809 | 0.76 | GRIN1 (0.41) | — | |
| SCHEMBL13680810 | 0.76 | HSD17B1 (0.53) | MEN1CYP1A2CYP3A4KMT2AHSD17B1 | |
| SCHEMBL2558804 | 0.76 | TRIM24 (0.60) | CYP4F2CYP4A11P4HTMMAP4K4KDM4E | |
| SCHEMBL13680805 | 0.75 | EPHX2 (0.55) | MEN1ALDH1A1CYP1A2CYP3A4GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |