Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PRNP | P04156 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371492 | 0.88 | RAB9A (0.51) | RAB9ALMNAKDM4EHPGDDRD2 | |
| SCHEMBL13681052 | 0.87 | HPGDS (0.54) | RAB9ALMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL13680926 | 0.84 | LMNA (0.56) | RAB9ALMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13680922 | 0.84 | GFER (0.62) | RAB9ALMNAKDM4EHSD17B10MAPT | |
| SCHEMBL13680943 | 0.84 | RAB9A (0.48) | RAB9ALMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL13680937 | 0.84 | KDM4E (0.52) | RAB9ALMNAKDM4EHPGDMAPT | |
| SCHEMBL7039927 | 0.84 | KDM4E (0.60) | RAB9ALMNAKDM4EHPGDMAPT | |
| SCHEMBL30785478 | 0.83 | KDM4E (0.54) | RAB9ALMNAKDM4EHPGDDRD2 | |
| SCHEMBL10031024 | 0.81 | LMNA (0.59) | RAB9ALMNAKDM4EHPGDDRD2 | |
| SCHEMBL13680930 | 0.81 | LMNA (0.55) | LMNAKDM4EMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |