Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680926 | 0.85 | LMNA (0.56) | RAB9AMAPTLMNAKDM4EPOLB | |
| SCHEMBL13680922 | 0.85 | GFER (0.62) | RAB9AMAPTLMNAKDM4EPOLB | |
| SCHEMBL13680920 | 0.84 | RAB9A (0.56) | RAB9AMAPTLMNAKDM4EPOLB | |
| SCHEMBL13680937 | 0.84 | KDM4E (0.52) | RAB9AMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL13680932 | 0.83 | KMT2A (0.47) | RAB9AMAPTLMNAKDM4EPOLB | |
| SCHEMBL13680945 | 0.83 | MEN1 (0.52) | RAB9AMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL13681055 | 0.82 | KDM4E (0.46) | RAB9AMAPTLMNAKDM4EPOLB | |
| SCHEMBL13681039 | 0.82 | MAPT (0.43) | RAB9AMAPTLMNAKDM4EPOLB | |
| SCHEMBL13681044 | 0.82 | MAPT (0.41) | RAB9AMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL13680930 | 0.81 | LMNA (0.55) | MAPTLMNAKDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |