Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680996 | 0.80 | QPCT (0.44) | — | |
| SCHEMBL13680995 | 0.80 | CDC25A (0.48) | SMN1; SMN2ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL13680624 | 0.77 | NPC1 (0.51) | RAB9ASMN1; SMN2NPC1POLBMEN1 | |
| SCHEMBL13680926 | 0.77 | LMNA (0.56) | RAB9ASMN1; SMN2NPC1POLBMEN1 | |
| SCHEMBL13680972 | 0.76 | ALDH1A1 (0.45) | RAB9ASMN1; SMN2NPC1POLBMEN1 | |
| SCHEMBL13680991 | 0.76 | PDE3B (0.48) | SMN1; SMN2POLBALDH1A1KDM4EGAA | |
| SCHEMBL13681003 | 0.75 | HRH3 (0.39) | SMN1; SMN2ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL13680986 | 0.75 | GUSB (0.45) | NPC1MAPTENPP2 | |
| SCHEMBL13680981 | 0.74 | GSK3B (0.46) | DYRK1A | |
| SCHEMBL13680955 | 0.73 | GAA (0.42) | RAB9ASMN1; SMN2NPC1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |