SCHEMBL13680996

SCHEMBL13680996

O=CCCc1csc(-c2ccc3nc[nH]c3c2)n1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 14/20 0.44
QPCTL Q9NXS2 13/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13680997 0.80 RAB9A (0.41)
SCHEMBL13680995 0.78 CDC25A (0.48)
SCHEMBL13680986 0.78 GUSB (0.45)
SCHEMBL13680991 0.77 PDE3B (0.48)
SCHEMBL13680981 0.75 GSK3B (0.46) QPCTQPCTL
SCHEMBL13680971 0.74 TERT (0.44) QPCTQPCTL
SCHEMBL13680626 0.74 QPCT (0.57) QPCTQPCTL
SCHEMBL13681003 0.74 HRH3 (0.39)
SCHEMBL13681061 0.74 LMNA (0.38)
SCHEMBL13680943 0.72 RAB9A (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582658-B2 Bicyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2009-09-01 US disclosed
US-7582658-B2 Bicyclic compound ASAHI KASEI PHARMA CORPORATION (JP) 2009-09-01 US disclosed