Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680971 | 0.78 | TERT (0.44) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL13680597 | 0.77 | ALDH1A1 (0.55) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL13680997 | 0.76 | RAB9A (0.41) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL13680976 | 0.76 | MAPT (0.50) | ALDH1A1KDM4EHPGDTERTMAPT | |
| SCHEMBL13680866 | 0.74 | ALDH1A1 (0.60) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL13680975 | 0.73 | PDE3B (0.48) | ALDH1A1SMN1; SMN2KDM4EHPGDPOLB | |
| SCHEMBL13680977 | 0.72 | CA12 (0.40) | ALDH1A1SMN1; SMN2NPC1KDM4EHPGD | |
| SCHEMBL13680904 | 0.72 | NPC1 (0.45) | NPC1HCRTR1MAPT | |
| SCHEMBL2457137 | 0.72 | RAB9A (0.67) | ALDH1A1RAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL13680899 | 0.71 | CYP2C19 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |