Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15051595 | 0.75 | KMT2A (0.34) | MEN1KMT2AGPR119SLC22A12HTT | |
| SCHEMBL18836575 | 0.74 | PLCG1 (0.43) | — | |
| SCHEMBL520070 | 0.74 | HTT (0.42) | MEN1KMT2AHTT | |
| SCHEMBL2112250 | 0.71 | CHRNB2 (0.33) | — | |
| SCHEMBL29953208 | 0.67 | HTT (0.42) | MEN1KMT2AHTT | |
| SCHEMBL4359777 | 0.67 | HTT (0.42) | MEN1KMT2AHTT | |
| SCHEMBL17099864 | 0.67 | LATS1 (0.33) | MEN1KMT2AGPR119SLC22A12HTT | |
| SCHEMBL16180174 | 0.66 | ENPP2 (0.50) | — | |
| SCHEMBL22366746 | 0.64 | AAK1 (0.38) | MEN1KMT2ASLC22A12 | |
| SCHEMBL121398 | 0.64 | DGAT1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190327974-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2019-10-31 | — | — | US | disclosed |
| WO-2018127928-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2018-07-12 | — | — | WO | disclosed |
| US-8673891-B2 | Aminopyrazine derivative and medicine | NIPPON SHINYAKU CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| EP-2394999-B1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO LTD (JP) | 2014-01-29 | — | — | EP | disclosed |
| US-8586591-B2 | Aminopyrazine derivative and medicine | NIPPON SHINYAKU CO., LTD. (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130131082-A1 | Aminopyrazine Derivative and Medicine | NIPPON SHINYAKU CO., LTD (JP) | 2013-05-23 | — | — | US | disclosed |
| EP-2394999-A1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110288065-A1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190327974-A1 | SYNERGISTS FOR IMPROVED PESTICIDES | BCHE, DDT, DBF4 | MEN1 604/4885KMT2A 1397/4885GPR119 2795/4885 |
| US-20130131082-A1 | Aminopyrazine Derivative and Medicine | MC2R, AGTR2, AGTR1 | MEN1 4588/4885KMT2A 1225/4885GPR119 424/4885 |
| US-20110288065-A1 | AMINOPYRAZINE DERIVATIVE AND MEDICINE | MC2R, CNR1, NPY2R | MEN1 4559/4885KMT2A 1474/4885GPR119 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.