Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUMO2 | P61956 | 1/20 | 0.40 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296863 | 0.81 | ALDH1A1 (0.42) | SUMO2SUMO1SENP7SENP2ALDH1A1 | |
| SCHEMBL4296989 | 0.80 | ALDH1A1 (0.42) | SUMO2SUMO1SENP7SENP2ALDH1A1 | |
| SCHEMBL3433055 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPK1CYP2C9CYP2C19CASP6 | |
| SCHEMBL1369157 | 0.72 | MEN1 (0.43) | SUMO2SUMO1SENP7SENP2ALDH1A1 | |
| SCHEMBL16361913 | 0.71 | MEN1 (0.43) | SUMO2SUMO1SENP7SENP2ALDH1A1 | |
| SCHEMBL304685 | 0.69 | CA1 (0.38) | ALDH1A1CASP6HSD17B10NT5EKDM4E | |
| SCHEMBL304686 | 0.69 | CA1 (0.38) | ALDH1A1CASP6HSD17B10NT5EKDM4E | |
| Potassium SCHEMBL4418575 | 0.68 | CA1 (0.38) | ALDH1A1CASP6HSD17B10NT5EKDM4E | |
| SCHEMBL560834 | 0.68 | CA1 (0.38) | ALDH1A1CASP6HSD17B10NT5EKDM4E | |
| SCHEMBL1368963 | 0.68 | SUMO2 (0.40) | SUMO2SUMO1SENP7SENP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916137-B2 | Monofunctional carbocyanine dyes for in vivo and in vitro imaging | THE GENERAL HOSPITAL CORPORATION (US) | 2014-12-23 | — | — | US | disclosed |
| US-20110286933-A1 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| WO-2010054330-A2 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | THE GENERAL HOSPITAL CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110286933-A1 | MONOFUNCTIONAL CARBOCYANINE DYES FOR IN VIVO AND IN VITRO IMAGING | MKI67, HCCS, PYCR1 | SUMO2 2724/4885SUMO1 1984/4885SENP7 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.