Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304685 | 1.00 | CA1 (0.38) | CA1CA2CA12CA7CA14 | |
| Potassium SCHEMBL4418575 | 0.98 | CA1 (0.38) | CA1CA2CA12CA7CA14 | |
| SCHEMBL560834 | 0.98 | CA1 (0.38) | CA1CA2CA12CA7CA14 | |
| SCHEMBL3433055 | 0.79 | ALDH1A1 (0.39) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6537392 | 0.78 | MAPT (0.36) | ARALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4296863 | 0.77 | ALDH1A1 (0.42) | SNCAALDH1A1HSD17B10TDP1KDM4E | |
| SCHEMBL4296989 | 0.76 | ALDH1A1 (0.42) | SNCAALDH1A1HSD17B10TDP1KDM4E | |
| SCHEMBL24725924 | 0.75 | MRGPRX2 (0.40) | AR | |
| SCHEMBL11326119 | 0.74 | AR (0.39) | CA1CA2CA12CA7AR | |
| SCHEMBL11516736 | 0.74 | ALDH1A1 (0.39) | CA1CA2CA12ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106496094-B | A kind of Heptamethine cyanines near-infrared fluorescent molecular probe and its preparation method and application | 东南大学 | 2019-05-31 | — | — | CN | claimed |
| CN-106496093-B | A kind of near-infrared fluorescent molecular probe and its synthetic method and application | 东南大学 | 2019-05-28 | — | — | CN | claimed |
| CN-106496093-A | A kind of near-infrared fluorescent molecular probe and its synthetic method and application | 东南大学 | 2017-03-15 | — | — | CN | claimed |
| CN-106496094-A | A kind of Heptamethine cyanines near-infrared fluorescent molecular probe and its preparation method and application | 东南大学 | 2017-03-15 | — | — | CN | claimed |
| US-20230117826-A1 | COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME | MOLECULAR TARGETING TECHNOLOGIES, INC. | 2023-04-20 | — | — | US | disclosed |
| WO-2022265043-A1 | COMPOUND AND LABELED BIOMATERIAL USING SAME | 富士フイルム株式会社 | 2022-12-22 | — | — | WO | disclosed |
| WO-2022129336-A1 | PH RESPONSIVE CYANINE DYES AND CONJUGATES THEREOF | BRACCO IMAGING SPA (IT) | 2022-06-23 | — | — | WO | disclosed |
| WO-2021158219-A1 | COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME | MOLECULAR TARGETING TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| US-10968386-B2 | Pentamethine cyanine dye and preparation method therefor | SHENZHEN UNIVERSITY (CN) | 2021-04-06 | — | — | US | disclosed |
| US-20200095499-A1 | PENTAMETHINE CYANINE DYE AND PREPARATION METHOD THEREFOR | SHENZHEN UNIVERSITY (CN) | 2020-03-26 | — | — | US | disclosed |
| CN-106496094-B | A kind of Heptamethine cyanines near-infrared fluorescent molecular probe and its preparation method and application | 东南大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-106496094-B | A kind of Heptamethine cyanines near-infrared fluorescent molecular probe and its preparation method and application | 东南大学 | 2019-05-31 | — | — | CN | disclosed |
| EP-1326649-A1 | TISSUE-SPECIFIC EXOGENOUS OPTICAL AGENTS | MALLINCKRODT INC. (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1326651-A2 | DYNAMIC ORGAN FUNCTION MONITORING AGENTS | Mallinckrodt Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| US-6579718-B1 | For detecting and quantifying peptides, polypeptides and proteins; sensitive, facile and does not require use of organic solvents | MOLECULAR PROBES, INC. | 2003-06-17 | — | — | US | disclosed |
| US-6538129-B1 | Luminescent compounds | Terpetschnig, Ewald A. | 2003-03-25 | — | — | US | disclosed |
| US-6498945-B1 | FREE RADICAL GENERATION OF WATER SOLUBLE POLYMER TO ENHANCE CYTOPATHOGENIC EFFICACY | AMERSHAM HEALTH AS (NO) | 2002-12-24 | — | — | US | disclosed |
| WO-2002032421-A1 | INDOLE COMPOUNDS AS MINIMALLY PHYSIOLOGIAL FUNCTION MONITIORING AGENTS | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032465-A1 | TISSUE-SPECIFIC EXOGENOUS OPTICAL AGENTS | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| WO-2002032860-A2 | DYNAMIC ORGAN FUNCTION MONITORING AGENTS | MALLINCKRODT INC. (US) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117826-A1 | COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME | ALDH1A2, PDE6C, ALDH1A3 | CA1 3362/4885CA2 1032/4885CA12 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.