Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899943 | 0.84 | ALDH1A1 (0.52) | TAS2R38CA2CA4CA5AGAA | |
| SCHEMBL3897654 | 0.82 | ALDH1A1 (0.50) | TAS2R38CA2CA4CA5AGAA | |
| SCHEMBL8887300 | 0.82 | SMN1; SMN2 (0.59) | CA2CA4ALDH1A1MAPTKMT2A | |
| SCHEMBL14511451 | 0.80 | TAS2R38 (0.75) | TAS2R38CA2CA4GAAALDH1A1 | |
| SCHEMBL13714954 | 0.78 | DGAT1 (0.44) | TAS2R38SRCGAAALDH1A1MAPT | |
| SCHEMBL13715092 | 0.76 | SRC (0.47) | TAS2R38CA2SRCALDH1A1MAPT | |
| SCHEMBL13715008 | 0.76 | ENPP2 (0.54) | TAS2R38SRCTSHR | |
| SCHEMBL28618160 | 0.76 | MAPT (0.57) | CA2CA4CA5ASRCALDH1A1 | |
| SCHEMBL13715088 | 0.75 | LTA4H (0.46) | TAS2R38CA2CA4CA5ASRC | |
| SCHEMBL11163447 | 0.74 | CA2 (0.54) | CA2CA4CA5AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572459-B2 | Prevention infections in humans, animals | STARPHARMA PTY LTD. (AU) | 2009-08-11 | — | — | US | disclosed |