Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5563464 | 0.89 | CNR1 (0.51) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL10965487 | 0.87 | CNR1 (0.53) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL6598292 | 0.87 | SLC6A2 (0.54) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL7596731 | 0.82 | ACP3 (0.57) | L3MBTL1CES2CES1KMT2ACNR1 | |
| SCHEMBL28248352 | 0.82 | ALDH1A1 (0.45) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL28243492 | 0.80 | TDP1 (0.42) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL1375360 | 0.79 | SRC (0.64) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL8731400 | 0.78 | TRPA1 (0.53) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| Diphenylacetic Acid SCHEMBL38022 | 0.78 | SRC (0.62) | TDP1L3MBTL1HDAC3HDAC4HDAC1 | |
| SCHEMBL465969 | 0.78 | TDP1 (0.61) | TDP1L3MBTL1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 907 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552931-B2 | Dihydroxy lactam based polymers, compositions and applications thereof | ISP INVESTMENTS LLC (US) | 2026-02-17 | — | — | US | claimed |
| CN-119838435-B | Composite reverse osmosis membrane and preparation method thereof | 湖南沁森高科新材料有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119838435-A | Composite reverse osmosis membrane and preparation method thereof | 湖南沁森高科新材料有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-117050393-A | High-elastic wear-resistant rubber backing plate and preparation method thereof | 台州大华铁路材料有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-114573721-B | Rapidly degradable biological plastic and preparation method thereof | 壹科环塑新材料科技(深圳)有限公司 | 2023-07-25 | — | — | CN | claimed |
| US-20220315761-A1 | DIHYDROXY LACTAM BASED POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF | ISP INVESTMENTS LLC (US) | 2022-10-06 | — | — | US | claimed |
| CN-114573721-A | Quickly degradable biological plastic and preparation method thereof | 今禾方吟科技(深圳)有限责任公司 | 2022-06-03 | — | — | CN | claimed |
| US-20220009899-A1 | PROCESS AND COMPOUNDS FOR PREPARATION OF CANNABINOIDS | EMBIO LIMITED (IN) | 2022-01-13 | — | — | US | claimed |
| EP-3914635-A1 | DIHYDROXY LACTAM BASED POLYMERS, COMPOSITIONS AND APPLICATIONS THEREOF | ISP Investments LLC (US) | 2021-12-01 | — | — | EP | claimed |
| CN-113631632-A | Dihydroxylactam-based polymers, compositions thereof and uses thereof | ISP投资有限公司 | 2021-11-09 | — | — | CN | claimed |
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| CN-102936215-A | Synthesizing method for 2-sulfydryl-N-(6-(3-arylurea) hexyl) amide | UNIV HUAIHUA | 2013-02-20 | — | — | CN | claimed |
| US-20100179136-A1 | N-AMINO TETRAHYDROTHIAZINE DERIVATIVES, METHOD OF MANUFACTURE AND USE | WOMEN & INFANTS HOSPITAL (US) | 2010-07-15 | — | — | US | claimed |
| EP-2114410-A2 | N-AMINO TETRAHYDROTHIAZINE DERIVATIVES, METHOD OF MANUFACTURE AND USE | Woman & Infants Hospital (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2008091946-A2 | N-AMINO TETRAHYDROTHIAZINE DERIVATIVES, METHOD OF MANUFACTURE AND USE | WOMEN & INFANTS HOSPITAL (US) | 2008-07-31 | — | — | WO | claimed |
| CN-1081631-C | N-methyl-N- [ (1S) -1-phenyl-2- ((3S) -3-hydroxypyrrolidin-1-yl ] ethyl ] -2, 2-diphenylacetamide | MERCK PATENT GMBH (DE) | 2002-03-27 | — | — | CN | claimed |
| EP-0761650-B1 | Thermally stable and storable crystalline modification of N-methyl-N-((1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)-ethyl)-2,2-diphenyl-acetamide and process for its preparation | MERCK PATENT GMBH (DE) | 2001-10-31 | — | — | EP | claimed |
| US-6060504-A | N-methyl-N-[(1S)-1-phenyl-2-(3S)-hydroxypyrrolidin-1-yl)ethyl]-2-2-diphenylacetamide | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-05-09 | — | — | US | claimed |
| CN-1151986-A | N-methyl-N- [ (1S) -1-phenyl-2- ((3S) -3-hydroxypyrrolidin-1-yl) ethyl ] -2, 2-diphenylacetamide | MERCK PATENT GMBH (DE) | 1997-06-18 | — | — | CN | claimed |
| EP-0761650-A1 | Thermally stable and storable crystalline modification of N-methyl-N-((1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)-ethyl)-2,2-diphenyl-acetamide and process for its preparation | MERCK PATENT GmbH (DE) | 1997-03-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12552931-B2 | Dihydroxy lactam based polymers, compositions and applications thereof | PARG, GNE, PGLS | TDP1 2543/4885L3MBTL1 2436/4885HDAC3 1776/4885 |
| US-20220009899-A1 | PROCESS AND COMPOUNDS FOR PREPARATION OF CANNABINOIDS | CNR2, CNR1, DEGS1 | TDP1 2924/4885L3MBTL1 3541/4885HDAC3 1250/4885 |
| US-20100179136-A1 | N-AMINO TETRAHYDROTHIAZINE DERIVATIVES, METHOD OF MANUFACTURE AND USE | NNMT, GNMT, BHMT2 | TDP1 2068/4885L3MBTL1 3896/4885HDAC3 2897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.