Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17260198 | 0.97 | KEAP1 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL17260194 | 0.97 | KEAP1 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL13926067 | 0.91 | — | — | |
| SCHEMBL18118867 | 0.90 | LMNA (0.34) | KEAP1NFE2L2 | |
| SCHEMBL13926065 | 0.89 | KEAP1 (0.33) | KEAP1NFE2L2 | |
| SCHEMBL2329207 | 0.85 | KEAP1 (0.40) | KEAP1NFE2L2ALOX5 | |
| SCHEMBL18114355 | 0.84 | ALDH1A1 (0.36) | KEAP1NFE2L2 | |
| SCHEMBL18118857 | 0.83 | RAB9A (0.36) | — | |
| SCHEMBL17260199 | 0.82 | KEAP1 (0.38) | KEAP1NFE2L2 | |
| SCHEMBL17260197 | 0.82 | KEAP1 (0.38) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170336416-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | ABBOTT LABORATORIES | 2017-11-23 | — | — | US | claimed |
| US-20150330986-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | ABBOTT LAB (US) | 2015-11-19 | — | — | US | claimed |
| US-20170336416-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | ABBOTT LABORATORIES | 2017-11-23 | — | — | US | disclosed |
| US-20150330986-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | ABBOTT LAB (US) | 2015-11-19 | — | — | US | disclosed |
| US-20090181359-A1 | METHOD OF PERFORMING ULTRA-SENSITIVE IMMUNOASSAYS | ABBOTT LABORATORIES | 2009-07-16 | — | — | US | disclosed |
| US-20090053736-A1 | Homogeneous Chemiluminescent Immunoassay for Analysis of Iron Metalloproteins | ABBOTT LABORATORIES | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150330986-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | APOB, MPO, LPO | KEAP1 1733/4885NFE2L2 885/4885ALOX5 177/4885 |
| US-20170336416-A1 | COMPOSITIONS FOR ENHANCING CHEMILUMINESCENCE AND METHODS OF USING THE SAME | APOB, MPO, LPO | KEAP1 1733/4885NFE2L2 885/4885ALOX5 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.