SCHEMBL1376899

SCHEMBL1376899

C[Si](C)(C)Oc1ccnc(O[Si](C)(C)C)n1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.32
CCR1 P32246 1/20 0.30
CCR5 P51681 1/20 0.30
CCR8 P51685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10017439 0.78 EDNRB (0.37)
SCHEMBL16260054 0.78 GRM4 (0.35) NUDT1
SCHEMBL19073173 0.77 NOS3 (0.31)
SCHEMBL10048540 0.77 SCN9A (0.47)
SCHEMBL8958798 0.77 SCN9A (0.33)
SCHEMBL10385800 0.74 CYP1A2 (0.41)
SCHEMBL8583850 0.74 GAA (0.35)
SCHEMBL10385773 0.74 NUDT1 (0.33) NUDT1
SCHEMBL12603734 0.72
SCHEMBL396081 0.72 MAPK8 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119786736-A Electrolyte additive composition, electrolyte and battery 惠州亿纬锂能股份有限公司 2025-04-08 CN claimed
CN-116199679-A Industrial preparation method of lamivudine 吉斯凯(苏州)制药有限公司 2023-06-02 CN claimed
EP-1819718-A1 DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF Sicor Inc. (US) 2007-08-22 EP claimed
US-20060173174-A1 Difluoronucleosides and process for preparation thereof SICOR, INC. 2006-08-03 US claimed
WO-2006063105-A1 DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF SICOR INC. (US) 2006-06-15 WO claimed
JP-1061495-A None JP disclosed
US-20260015338-A1 TARGETED PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2026-01-15 US disclosed
US-12454521-B2 Targeted protein degradation C4 THERAPEUTICS, INC. 2025-10-28 US disclosed
WO-2025072862-A9 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2025-06-26 WO disclosed
US-20250145654-A1 COMPOUNDS AND METHODS FOR TREATING DISEASE ROME THERAPEUTICS, INC. 2025-05-08 US disclosed
CN-119786736-A Electrolyte additive composition, electrolyte and battery 惠州亿纬锂能股份有限公司 2025-04-08 CN disclosed
CN-119786736-A Electrolyte additive composition, electrolyte and battery 惠州亿纬锂能股份有限公司 2025-04-08 CN disclosed
US-4851423-A Pharmaceutically active compounds SCHERING CORPORATION (US) 1989-07-25 US disclosed
EP-0300765-A2 Process for preparing 2-deoxynucleosides ETHYL CORPORATION (US) 1989-01-25 EP disclosed
US-4594339-A Veterinary medicine SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1986-06-10 US disclosed
EP-0010205-B1 5-SUBSTITUTED 1-(2'-DEOXY-2'-SUBSTITUTED-BETA-D-ARABINOFURANOSYL) PYRIMIDINE NUCLEOSIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Sloan-Kettering Institute For Cancer Research (US) 1983-05-04 EP disclosed
US-4211773-A VIRICIDES, ANTITUMOR AGENTS SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1980-07-08 US disclosed
EP-0010205-A1 5-Substituted 1-(2'-deoxy-2'-substituted-beta-D-arabinofuranosyl) pyrimidine nucleosides and pharmaceutical compositions containing them Sloan-Kettering Institute For Cancer Research (US) 1980-04-30 EP disclosed
US-4109078-A N-(POLYSACCHARIDYL)-NITROGEN HETEROCYCLES, ESPECIALLY PYRIMIDINE OR PURINE BASES, AND PROCESS FOR THEIR PREPARATION SCHERING AKTIENGESELLSCHAFT (DE) 1978-08-22 US disclosed
US-4082911-A PROCESS FOR THE PREPARATION OF NUCLEOSIDES SCHERING AKTIENGESELLSCHAFT (DT) 1978-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015338-A1 TARGETED PROTEIN DEGRADATION PSMC3, PSMA6, ADRM1 NUDT1 4795/4885CCR1 534/4885CCR5 1923/4885
US-20060173174-A1 Difluoronucleosides and process for preparation thereof DUT, NUDT1, DPYD NUDT1 2/4885CCR1 3039/4885CCR5 3583/4885
US-12454521-B2 Targeted protein degradation STUB1, MDM2, UBE3A NUDT1 4574/4885CCR1 4280/4885CCR5 4347/4885
US-20250145654-A1 COMPOUNDS AND METHODS FOR TREATING DISEASE EHMT1, POLRMT, RNASE1 NUDT1 325/4885CCR1 587/4885CCR5 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.