SCHEMBL137794

SCHEMBL137794

C=C(C)C(=O)OC(CC)[SiH2]C(OCC)OCC

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.35
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537068 0.87 THRB (0.38) THRBTSHRALDH1A1
SCHEMBL136874 0.85 ALDH1A1 (0.38) THRBTSHRALDH1A1
SCHEMBL140537 0.84 TSHR (0.41) THRBTSHRALDH1A1
SCHEMBL16537550 0.84 TSHR (0.41) THRBTSHR
SCHEMBL8839173 0.82 TSHR (0.33) TSHRALDH1A1
SCHEMBL137901 0.82 TSHR (0.37) THRBTSHRALDH1A1
SCHEMBL16536969 0.81 TSHR (0.34) THRBTSHR
SCHEMBL16537028 0.81 THRB (0.41) THRBTSHRALDH1A1
SCHEMBL4512356 0.81 TSHR (0.41) THRBTSHRALDH1A1
SCHEMBL1274038 0.81 TSHR (0.33) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025084741-A1 POLYOLEFIN GRAFT COPOLYMER PRODUCED USING INITIATOR CONTAINING AZIDOFORMATE GROUP AND PRODUCTION METHOD THEREFOR 세종대학교산학협력단 2025-04-24 WO claimed
CN-119331159-A Active organosilicon modified acrylic emulsion, preparation method and application thereof 河南高速公路发展有限责任公司潢淮分公司 2025-01-21 CN claimed
CN-112533910-B Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2024-05-10 CN claimed
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof BOSTIK SA (FR) 2023-12-05 US claimed
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF UNIVERSITE DE RENNES (FR) 2021-06-17 US claimed
EP-3802510-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF Bostik SA (FR) 2021-04-14 EP claimed
CN-112533910-A Monoethylenically unsaturated monomers and their use 博斯蒂克股份公司 2021-03-19 CN claimed
CN-106854259-B A kind of water-base drilling fluid fluid loss additive and preparation method thereof 中国石油化工股份有限公司 2019-03-29 CN claimed
EP-1675880-B1 METHOD FOR PARTIAL OR TOTAL OXIDATION OF ONE OR SEVERAL THIOCARBONYLTHIO ENDS OF A POLYMER OBTAINED BY RADICAL POLYMERISATION CONTROLLED BY REVERSIBLE ADDITION-CLEAVAGE RHODIA CHIMIE SA (FR) 2019-03-13 EP claimed
US-20170298026-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-10-19 US claimed
WO-2003040218-A1 POROUS POLYMER FILMS POLYMERAT PTY LTD (AU) 2003-05-15 WO claimed
US-20030088028-A1 Methods of polymerization ANTEO TECHNOLOGIES PTY LTD (AU) 2003-05-08 US claimed
WO-2002079305-A1 A METHOD OF TREATING THE SURFACE OF A SUBSTRATE POLYMER USEFUL FOR GRAFT POLYMERIZATION POLYMERAT PTY LTD (AU) 2002-10-10 WO claimed
US-6376615-B1 USING FREE RADICALS CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) 2002-04-23 US claimed
CN-1082966-C Polymer synthesis DU PONT (US) 2002-04-17 CN claimed
US-6291620-B1 Polymer synthesis E. I. DU PONT DE NEMOURS AND COMPANY 2001-09-18 US claimed
EP-0791016-B1 POLYMER SYNTHESIS DU PONT (US) 2000-07-12 EP claimed
CN-1162962-A Polymer synthesis DU PONT (US) 1997-10-22 CN claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof MEP1A, MEP1B, ALOX5 THRB 4861/4885TSHR 4885/4885ALDH1A1 581/4885
US-20170298026-A1 ALL PURPOSE RAFT AGENT NPC1L1, RFTN1, SGMS2 THRB 4068/4885TSHR 4058/4885ALDH1A1 817/4885
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF MEP1A, MEP1B, ALOX5 THRB 4861/4885TSHR 4885/4885ALDH1A1 581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.