Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359290 | 0.90 | DHPS (0.44) | DHPSHPGDHTTCHRNA7PPARG | |
| SCHEMBL13811161 | 0.88 | DHPS (0.43) | DHPSHPGDHTTCHRNA7HTR3A | |
| SCHEMBL13797975 | 0.88 | MAPK14 (0.55) | HPGDHTTPPARGMAPK14RAB9A | |
| SCHEMBL13359291 | 0.86 | SMN1; SMN2 (0.51) | DHPSHPGDHTTNPC1RAB9A | |
| SCHEMBL13359266 | 0.84 | MAPK14 (0.59) | DHPSHPGDHTTPPARGHDAC3 | |
| SCHEMBL13359225 | 0.81 | HTT (0.52) | HPGDHTTNPC1RAB9AKDM4E | |
| SCHEMBL13797993 | 0.78 | MAPK14 (0.74) | MAPK14LYNMAPK9 | |
| SCHEMBL13359167 | 0.75 | MAPK14 (0.54) | HPGDHTTPPARGHDAC3HDAC4 | |
| SCHEMBL20436796 | 0.75 | PPARG (0.63) | HPGDHTTPPARGRAB9AKDM4E | |
| SCHEMBL15384380 | 0.73 | HPGD (0.55) | HPGDCHRNA7HTR3APPARGHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550461-B2 | Benzofuran and benzothiophene compounds useful in treating cytokine mediated diseases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |