Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380517 | 0.87 | L3MBTL1 (0.37) | HTR6HTR7KDM4EHSD17B10SCN9A | |
| SCHEMBL1381623 | 0.86 | HTR6 (0.41) | ALDH1A1GAAHTR6TP53HTR7 | |
| SCHEMBL1380633 | 0.82 | HSD11B1 (0.41) | HTR6LMNAHTR7RAD52UBE2N | |
| SCHEMBL1380174 | 0.80 | RAD52 (0.36) | HTR6HTR7RAD52UBE2NL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1379813 | 0.78 | HTR6 (0.47) | ALDH1A1GAAHTR6MAPK1KDM4E | |
| SCHEMBL3627476 | 0.74 | MEN1 (0.53) | ALDH1A1GAAHTR6MAPK1HTR7 | |
| SCHEMBL1613495 | 0.71 | ABCB1 (0.38) | HTR6HTR7MEN1KMT2A | |
| SCHEMBL9106472 | 0.69 | HTR6 (0.46) | HTR6 | |
| SCHEMBL6637840 | 0.66 | HTR2C (0.51) | HTR6 | |
| SCHEMBL616801 | 0.66 | HTR6 (0.41) | ALDH1A1HTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| EP-1412325-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002100822-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2002-12-19 | — | — | WO | claimed |