Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 6/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1380517 | 0.81 | L3MBTL1 (0.37) | RAD52UBE2NL3MBTL1HTR6HTR1A | |
| SCHEMBL1380633 | 0.81 | HSD11B1 (0.41) | RAD52UBE2NL3MBTL1HTR6HTR1A | |
| SCHEMBL1379816 | 0.80 | ALDH1A1 (0.37) | RAD52UBE2NL3MBTL1HTR6HTR7 | |
| SCHEMBL1381623 | 0.80 | HTR6 (0.41) | RAD52UBE2NL3MBTL1HTR6HTR1A | |
| Trifluoroacetic Acid SCHEMBL1380171 | 0.76 | L3MBTL1 (0.43) | RAD52UBE2NL3MBTL1HTR6HTR1A | |
| SCHEMBL3619544 | 0.72 | PRKD1 (0.44) | HTR6HTR1ADRD2HTR7PRKD1 | |
| Trifluoroacetic Acid SCHEMBL1379813 | 0.64 | HTR6 (0.47) | HTR6 | |
| SCHEMBL7045566 | 0.64 | PRKD1 (0.49) | HTR6HTR1ADRD2HTR7EPHX2 | |
| SCHEMBL10571731 | 0.64 | PRKD1 (0.49) | L3MBTL1EPHX2PRKD1PIK3CDHTR2A | |
| SCHEMBL6637840 | 0.64 | HTR2C (0.51) | HTR6HTR1ADRD2EPHX2PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| EP-1412325-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002100822-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2002-12-19 | — | — | WO | claimed |