Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20072258 | 0.89 | CES2 (0.38) | PDE2ACES2NOTUMAREGLN1 | |
| SCHEMBL19507808 | 0.87 | PDE2A (0.37) | PDE2ACES2GABRA1GABRG2GABRB3 | |
| SCHEMBL16405335 | 0.82 | RAPGEF4 (0.35) | PDE2ACES2AREGLN1CACNA1H | |
| SCHEMBL21139479 | 0.80 | PDE2A (0.41) | PDE2ACES2AREGLN1CACNA1H | |
| SCHEMBL26938094 | 0.80 | PDE2A (0.34) | PDE2ACES2NOTUMAREGLN1 | |
| SCHEMBL23547617 | 0.80 | PDE2A (0.37) | PDE2ACES2NOTUMAREGLN1 | |
| SCHEMBL21139491 | 0.80 | PDE2A (0.44) | PDE2AGABRA1GABRG2GABRB3P2RX7 | |
| SCHEMBL29316639 | 0.78 | CA1 (0.43) | PDE2ACES2NOTUMGABRA1GABRG2 | |
| SCHEMBL15934972 | 0.78 | P2RX7 (0.43) | PDE2ACES2NOTUMAREGLN1 | |
| SCHEMBL24910409 | 0.76 | IKBKB (0.38) | PDE2ACES2NOTUMGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090145483-A1 | Novel electroluminescent compounds and organic electroluminescent device suing the same | GRACEL DISPLAY INC. (KR) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090145483-A1 | Novel electroluminescent compounds and organic electroluminescent device suing the same | LEF1, ODC1, AOC2 | PDE2A 3564/4885CES2 1255/4885NOTUM 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.