Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454798 | 0.82 | MAPT (0.49) | HTTMAPTGAAALDH1A1HPGD | |
| SCHEMBL2453874 | 0.78 | PRMT6 (0.41) | PTGS2PTGS1TSHRCYP3A4CYP2C9 | |
| SCHEMBL2458498 | 0.77 | MAPT (0.47) | HTTMAPTGAAALDH1A1HPGD | |
| SCHEMBL14996612 | 0.72 | MAPT (0.48) | PTGS2PTGS1TSHRMAPTPDPK1 | |
| SCHEMBL27978182 | 0.71 | PTGS2 (0.38) | PTGS2PTGS1TSHRCYP3A4CYP2C9 | |
| SCHEMBL14996549 | 0.70 | PTGS1 (0.46) | PTGS2PTGS1TSHRCYP3A4CYP2C9 | |
| SCHEMBL14996596 | 0.69 | STIM1 (0.43) | PTGS2PTGS1TSHRMAPTALDH1A1 | |
| SCHEMBL10698854 | 0.69 | GABRB3 (0.50) | — | |
| SCHEMBL14996677 | 0.68 | MAPT (0.50) | PTGS2PTGS1TSHRMAPTALDH1A1 | |
| SCHEMBL14996589 | 0.68 | MAPT (0.44) | PTGS2PTGS1TSHRMAPTPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | PTGS2 577/4885PTGS1 1335/4885TSHR 2386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.