Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458498 | 0.92 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2455429 | 0.83 | ALDH1A1 (0.48) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL13809576 | 0.82 | PTGS2 (0.49) | MAPTHTTALDH1A1KMT2AGAA | |
| SCHEMBL12770967 | 0.72 | POLB (0.64) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL10812874 | 0.71 | MAPT (0.52) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2455752 | 0.68 | MEN1 (0.44) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2457134 | 0.68 | ALDH1A1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL2456915 | 0.68 | NOTUM (0.50) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL2453912 | 0.68 | KDM4E (0.42) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2453874 | 0.67 | PRMT6 (0.41) | MAPTNPC1SMN1; SMN2HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958948-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-10-05 | — | — | EP | disclosed |
| EP-1958948-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-8022073-B2 | Substituted pyridazine compounds and fungicidal uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1958948-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| EP-1958948-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156608-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | MAPT 285/4885NPC1 1560/4885RAB9A 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.