Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | GRM5 | P41594 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812763 | 0.87 | GRM5 (0.53) | RAB9ANPC1GRM5MAPTTP53 | |
| SCHEMBL13812801 | 0.84 | GRM5 (0.48) | RAB9ANPC1GRM5MAPTTP53 | |
| SCHEMBL13812946 | 0.83 | FADS1 (0.54) | RAB9ANPC1GRM5MAPTMEN1 | |
| SCHEMBL13812800 | 0.82 | KDM4E (0.50) | RAB9ANPC1GRM5MAPTTP53 | |
| SCHEMBL13812742 | 0.82 | KCNK3 (0.56) | RAB9ANPC1MAPTTP53THRB | |
| SCHEMBL13812798 | 0.81 | G6PD (0.48) | RAB9AGRM5MAPTMEN1KMT2A | |
| SCHEMBL13812765 | 0.81 | KCNK3 (0.55) | RAB9ANPC1MAPTTP53THRB | |
| SCHEMBL4250684 | 0.81 | NPC1 (1.00) | RAB9ANPC1GRM5MAPTTP53 | |
| SCHEMBL13812950 | 0.80 | RAB9A (0.58) | RAB9ANPC1MAPTTP53KMT2A | |
| SCHEMBL13812931 | 0.80 | ALDH1A1 (0.49) | GRM5MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |