SCHEMBL27245264

SCHEMBL27245264

N#Cc1c(N(c2ccccc2)c2ccccc2)c(F)c(N(c2ccccc2)c2ccccc2)c(C#N)c1N(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CTSK P43235 1/20 0.36
ALDH1A1 P00352 6/20 0.35
KDM4E B2RXH2 3/20 0.35
TDP1 Q9NUW8 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ADORA1 P30542 5/20 0.33
ADORA2A P29274 4/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13826136 0.96 MAPT (0.38) MAPTTSHRLMNASMN1; SMN2CTSK
SCHEMBL13826028 0.89 MAPT (0.43) MAPTTSHRLMNASMN1; SMN2CTSK
SCHEMBL22124615 0.85 ADORA1 (0.40) KDM4ENPSR1ADORA1ADORA2AMEN1
SCHEMBL29176116 0.85 MAPT (0.41) MAPTTSHRLMNASMN1; SMN2CTSK
SCHEMBL13826009 0.80 ALDH1A1 (0.44) MAPTTSHRALDH1A1KDM4ETDP1
SCHEMBL16122511 0.77 ADORA1 (0.36) MAPTTSHRLMNASMN1; SMN2ALDH1A1
SCHEMBL20657775 0.76 ALDH1A1 (0.48) MAPTTSHRLMNASMN1; SMN2CTSK
SCHEMBL31145578 0.76 MAPT (0.38) MAPTTSHRLMNASMN1; SMN2CTSK
SCHEMBL2453584 0.76 MAPT (0.34) MAPTTSHRLMNASMN1; SMN2CTSK
SCHEMBL21972989 0.74 HSD17B10 (0.43) MAPTTSHRLMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010810-A The method comprises the following steps of18F-marked difluoromethyl seleno ether compound, and synthetic method and application thereof 江苏省原子医学研究所 2026-05-12 CN claimed
CN-119241447-A Method for synthesizing quinazolinone and derivative thereof through photocatalysis three-component serial reaction 淮阴工学院 2025-01-03 CN claimed
CN-118638109-A Preparation method of opium drug-oxelidine 中山大学 2024-09-13 CN claimed
CN-118373786-A Method for synthesizing benzothiadiazine-1, 1-dioxide derivative by metal-free photocatalytic oxidation 淮阴工学院 2024-07-23 CN claimed
CN-117924125-A Method for preparing sulfonamide derivative through visible light catalysis without metal participation 苏州大学 2024-04-26 CN claimed
CN-117623925-A Method for deoxidizing and converting photocatalytic alcohol 同济大学 2024-03-01 CN claimed
CN-117164533-A Method for synthesizing furylacetic acid compound by using carbon dioxide 中国科学院兰州化学物理研究所 2023-12-05 CN claimed
CN-116332712-A Asymmetric deuterium functionalization method for chiral mercaptan and deuterium water promoted olefin 上海交通大学 2023-06-27 CN claimed
CN-116284009-A Method for continuously preparing 4, 5-imidazolinyl spiro pyrazolone compound by utilizing photocatalysis microchannel 南京先进生物材料与过程装备研究院有限公司 2023-06-23 CN claimed
CN-116023401-A Preparation method of chiral borate compound 同济大学 2023-04-28 CN claimed
US-20260132316-A1 ULTRAVIOLET DETACHABLE ADHESIVE COMPOSITION, ADHESIVE FILM PREPARED USING SAME, AND METHOD FOR PEELING OFF ADHESIVE FILM SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2026-05-14 US disclosed
CN-122010810-A The method comprises the following steps of18F-marked difluoromethyl seleno ether compound, and synthetic method and application thereof 江苏省原子医学研究所 2026-05-12 CN disclosed
EP-4726005-A1 ULTRAVIOLET DETACHABLE ADHESIVE COMPOSITION, ADHESIVE FILM PREPARED USING SAME, AND METHOD FOR PEELING OFF ADHESIVE FILM Seoul National University R&DB Foundation (KR) 2026-04-15 EP disclosed
US-20260071098-A1 ULTRAVIOLET-BLOCKING ADHESIVE COMPOSITION, METHOD FOR PREPARING ADHESIVE RESIN BY USING SAME, AND ADHESIVE FILM MANUFACTURED USING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2026-03-12 US disclosed
US-20260055128-A1 ORGANONICKEL INTERMEDIATES USEFUL FOR CARBOXYLATION OF SUBSTRATES WITH CARBON DIOXIDE U.S. DEPARTMENT OF ENERGY 2026-02-26 US disclosed
CN-117623925-A Method for deoxidizing and converting photocatalytic alcohol 同济大学 2024-03-01 CN disclosed
CN-116332712-A Asymmetric deuterium functionalization method for chiral mercaptan and deuterium water promoted olefin 上海交通大学 2023-06-27 CN disclosed
CN-116284009-A Method for continuously preparing 4, 5-imidazolinyl spiro pyrazolone compound by utilizing photocatalysis microchannel 南京先进生物材料与过程装备研究院有限公司 2023-06-23 CN disclosed
CN-116023401-A Preparation method of chiral borate compound 同济大学 2023-04-28 CN disclosed
US-20220324895-A1 DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER UNIV NEW YORK (US) 2022-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132316-A1 ULTRAVIOLET DETACHABLE ADHESIVE COMPOSITION, ADHESIVE FILM PREPARED USING SAME, AND METHOD FOR PEELING OFF ADHESIVE FILM CDH1, ICAM1, RAD51 MAPT 1907/4885TSHR 2972/4885LMNA 41/4885
US-20260071098-A1 ULTRAVIOLET-BLOCKING ADHESIVE COMPOSITION, METHOD FOR PREPARING ADHESIVE RESIN BY USING SAME, AND ADHESIVE FILM MANUFACTURED USING SAME CDH1, ITGAM, ICAM1 MAPT 970/4885TSHR 2711/4885LMNA 561/4885
US-20260055128-A1 ORGANONICKEL INTERMEDIATES USEFUL FOR CARBOXYLATION OF SUBSTRATES WITH CARBON DIOXIDE MT-CO2, SCO2, ACACA MAPT 3729/4885TSHR 4322/4885LMNA 4716/4885
US-20220324895-A1 DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER ALG1, PPOX, MANBA MAPT 1083/4885TSHR 4266/4885LMNA 1761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.