Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383520 | 0.89 | THRB (0.52) | HDAC3HDAC1HDAC2HDAC6THRB | |
| SCHEMBL1383227 | 0.84 | ALDH1A1 (0.42) | LMNAHTTHDAC3HDAC1HDAC2 | |
| SCHEMBL3442663 | 0.78 | HDAC3 (0.52) | LMNAHTTHDAC3HDAC1HDAC2 | |
| SCHEMBL1384191 | 0.76 | CASR (0.55) | LMNATHRBALDH1A1MAPTCASR | |
| SCHEMBL4112185 | 0.75 | NPY5R (0.44) | LMNAHTTHDAC3HDAC1HDAC2 | |
| SCHEMBL3442955 | 0.64 | ATM (0.57) | HDAC3HDAC1HDAC2HDAC6THRB | |
| SCHEMBL6135245 | 0.64 | CCNA2 (0.40) | HDAC3HDAC1HDAC2HDAC6MERTK | |
| SCHEMBL8224027 | 0.64 | HDAC3 (0.55) | HTTHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL27562638 | 0.64 | NAMPT (0.51) | LMNAHTTTYRO3KDM4ENAMPT | |
| SCHEMBL22573389 | 0.63 | LMNA (0.60) | LMNAHTTALDH1A1KDM4ENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4825686-B2 | — | — | 2011-11-30 | — | — | JP | claimed |