SCHEMBL13855543

SCHEMBL13855543

O=C(NCCCOCCCN[C@H]1OC(CO)[C@@H](O[C@H]2OC(CO)[C@@H](O)[C@H](O)C2O)[C@H](O)C1O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 1/20 0.45
▸ FGF2 P09038 1/20 0.45
▸ VEGFA P15692 1/20 0.45
▸ HPSE Q9Y251 1/20 0.45
▸ CA12 O43570 8/20 0.44
▸ CA1 P00915 8/20 0.44
▸ CA2 P00918 8/20 0.44
▸ CA9 Q16790 8/20 0.44
▸ CA14 Q9ULX7 8/20 0.44
▸ LMNA P02545 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ HRAS P01112 1/20 0.43
▸ LGALS8 O00214 1/20 0.41
▸ SLC6A2 P23975 1/20 0.40
▸ HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12094119 0.84 LGALS3 (0.54) FGF1FGF2VEGFAHPSEHRAS
SCHEMBL12094113 0.84 LGALS3 (0.54) FGF1FGF2VEGFAHPSEHRAS
SCHEMBL19036050 0.84 LGALS3 (0.54) FGF1FGF2VEGFAHPSEHRAS
SCHEMBL31695082 0.84 HRAS (0.48) FGF1FGF2VEGFAHPSECA12
SCHEMBL18756738 0.81 HTT (0.50) LMNASMN1; SMN2LGALS8HTT
SCHEMBL8985399 0.78 TGM2 (0.49) LMNASMN1; SMN2LGALS8HTT
SCHEMBL28333071 0.77 LMNA (0.54) LMNASMN1; SMN2LGALS8HTT
SCHEMBL13855545 0.76 FGF1 (0.38) FGF1FGF2VEGFAHPSECA12
SCHEMBL11435111 0.75 HTT (0.50) HTT
SCHEMBL4969178 0.74 HRAS (0.43) FGF1FGF2VEGFAHPSEHRAS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8647613-B2 Drug carrier JCR PHARMACEUTICALS CO., LTD. (JP) 2014-02-11 — — US disclosed
US-20090136443-A1 Drug Carrier OXGENIX CO., LTD. (JP) 2009-05-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090136443-A1 Drug Carrier ABCB11, SLC47A1, SLC47A2 FGF1 1359/4885FGF2 665/4885VEGFA 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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