Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389462 | 1.00 | GRIK1 (0.35) | GRIK1ALDH1A1TSHREP300SMN1; SMN2 | |
| SCHEMBL11973153 | 0.76 | EP300 (0.43) | TSHREP300CA1 | |
| SCHEMBL11973156 | 0.76 | EP300 (0.43) | TSHREP300CA1 | |
| SCHEMBL11972799 | 0.74 | EP300 (0.47) | TSHREP300 | |
| SCHEMBL11972801 | 0.74 | EP300 (0.47) | TSHREP300 | |
| SCHEMBL21424872 | 0.74 | EP300 (0.34) | GRIK1ALDH1A1TSHREP300 | |
| SCHEMBL12987113 | 0.73 | GRIK1 (0.36) | GRIK1ALDH1A1TSHREP300MEN1 | |
| SCHEMBL12987110 | 0.73 | GRIK1 (0.36) | GRIK1ALDH1A1TSHREP300MEN1 | |
| SCHEMBL9997707 | 0.70 | ALDH1A1 (0.44) | GRIK1ALDH1A1EP300CA1LMNA | |
| SCHEMBL8473354 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673332-B1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEM PATENTS INC (US) | 2015-06-17 | — | — | EP | claimed |
| US-20120253059-A1 | Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-10-04 | — | — | US | claimed |
| US-20120010426-A1 | Processes Related to the Hydroformylation of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-01-12 | — | — | US | claimed |
| US-20110137071-A1 | Processes Related To The Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-06-09 | — | — | US | claimed |
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-05-17 | — | — | US | claimed |
| EP-1673332-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | ExxonMobil Chemical Patents Inc. (US) | 2006-06-28 | — | — | EP | claimed |
| WO-2005028407-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-03-31 | — | — | WO | claimed |
| CN-114618491-A | Preparation method of copper-based catalyst and method for preparing alkanol by catalytic hydrogenation of copper-based catalyst | 北京石油化工学院 | 2022-06-14 | — | — | CN | disclosed |
| EP-1673332-B1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEM PATENTS INC (US) | 2015-06-17 | — | — | EP | disclosed |
| US-8921607-B2 | Hydroformylation of butenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120253059-A1 | Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-10-04 | — | — | US | disclosed |
| US-8178730-B2 | Processes related to the hydroformylation of butenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20120010426-A1 | Processes Related to the Hydroformylation of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-01-12 | — | — | US | disclosed |
| US-8049043-B2 | Processes related to the hydroformylation of butenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-11-01 | — | — | US | disclosed |
| US-8022256-B2 | Hydroformylation of butenes comprising isobutylene | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-20110137071-A1 | Processes Related To The Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-06-09 | — | — | US | disclosed |
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-05-17 | — | — | US | disclosed |
| EP-1673332-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | ExxonMobil Chemical Patents Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005028407-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120253059-A1 | Hydroformylation Of Butenes | HMOX2, BBOX1, HMOX1 | GRIK1 3974/4885ALDH1A1 53/4885TSHR 4874/4885 |
| US-20120010426-A1 | Processes Related to the Hydroformylation of Butenes | GRHPR, BLVRB, DHPS | GRIK1 2662/4885ALDH1A1 37/4885TSHR 4871/4885 |
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | HMOX2, BBOX1, HMOX1 | GRIK1 3844/4885ALDH1A1 81/4885TSHR 4884/4885 |
| US-20110137071-A1 | Processes Related To The Hydroformylation Of Butenes | GRHPR, BLVRB, DHPS | GRIK1 2662/4885ALDH1A1 37/4885TSHR 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.