Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3058981 | 0.97 | — | — | |
| SCHEMBL1199397 | 0.97 | — | — | |
| SCHEMBL50857 | 0.97 | — | — | |
| Ethane SCHEMBL28105770 | 0.95 | GABRP (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2803021 | 0.93 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2801292 | 0.89 | MAPT (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8812366 | 0.89 | MAPT (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2801432 | 0.89 | MAPT (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL232192 | 0.87 | MAPT (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2801314 | 0.87 | MAPT (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673332-B1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEM PATENTS INC (US) | 2015-06-17 | — | — | EP | claimed |
| US-20120253059-A1 | Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-10-04 | — | — | US | claimed |
| US-8178730-B2 | Processes related to the hydroformylation of butenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-15 | — | — | US | claimed |
| US-20120010426-A1 | Processes Related to the Hydroformylation of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-01-12 | — | — | US | claimed |
| US-20110137071-A1 | Processes Related To The Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-06-09 | — | — | US | claimed |
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-05-17 | — | — | US | claimed |
| EP-1673332-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | ExxonMobil Chemical Patents Inc. (US) | 2006-06-28 | — | — | EP | claimed |
| WO-2005028407-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-03-31 | — | — | WO | claimed |
| EP-1673332-B1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEM PATENTS INC (US) | 2015-06-17 | — | — | EP | disclosed |
| US-8921607-B2 | Hydroformylation of butenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20120253059-A1 | Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-10-04 | — | — | US | disclosed |
| US-8178730-B2 | Processes related to the hydroformylation of butenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20120010426-A1 | Processes Related to the Hydroformylation of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-01-12 | — | — | US | disclosed |
| US-8049043-B2 | Processes related to the hydroformylation of butenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-11-01 | — | — | US | disclosed |
| US-8022256-B2 | Hydroformylation of butenes comprising isobutylene | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-20110137071-A1 | Processes Related To The Hydroformylation Of Butenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-06-09 | — | — | US | disclosed |
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-05-17 | — | — | US | disclosed |
| EP-1673332-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | ExxonMobil Chemical Patents Inc. (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005028407-A1 | HYDROFORMYLATION OF BUTENES COMPRISING ISOBUTYLENE | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120253059-A1 | Hydroformylation Of Butenes | HMOX2, BBOX1, HMOX1 | GABRP 1328/4885GABRD 1044/4885GABRA1 498/4885 |
| US-20120010426-A1 | Processes Related to the Hydroformylation of Butenes | GRHPR, BLVRB, DHPS | GABRP 1441/4885GABRD 818/4885GABRA1 495/4885 |
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | HMOX2, BBOX1, HMOX1 | GABRP 1129/4885GABRD 966/4885GABRA1 488/4885 |
| US-20110137071-A1 | Processes Related To The Hydroformylation Of Butenes | GRHPR, BLVRB, DHPS | GABRP 1441/4885GABRD 818/4885GABRA1 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.