Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898537 | 0.83 | LMNA (0.58) | LMNASMN1; SMN2ALDH1A1KDM4EKDM1A | |
| SCHEMBL3896702 | 0.83 | LMNA (0.58) | LMNASMN1; SMN2ALDH1A1KDM4EKDM1A | |
| SCHEMBL7475866 | 0.82 | MMP3 (0.51) | LMNASMN1; SMN2EPHX2ALDH1A1MEN1 | |
| SCHEMBL3894318 | 0.78 | ALDH1A1 (0.50) | LMNASMN1; SMN2POLBMAPK1HTT | |
| SCHEMBL13898312 | 0.77 | DRD2 (0.49) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL3893429 | 0.77 | DRD2 (0.49) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL3894096 | 0.76 | DRD2 (0.56) | LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL3891373 | 0.75 | ALDH1A1 (0.53) | LMNASMN1; SMN2POLBMAPK1HTT | |
| SCHEMBL14747464 | 0.71 | KDM1A (0.46) | SMN1; SMN2EPHX2KDM1AMAOB | |
| SCHEMBL2776196 | 0.71 | SMN1; SMN2 (0.55) | SMN1; SMN2EPHX2KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-7498344-B2 | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |