Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.41 |
| ▸ | CDK9 | P50750 | 9/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9610888 | 0.81 | CDK2 (0.39) | CDK2CDK9NAMPTTSHR | |
| SCHEMBL121954 | 0.80 | ALDH1A1 (0.43) | CDK2CDK9ALDH1A1MAPTKMT2A | |
| SCHEMBL18231808 | 0.80 | CDK2 (0.36) | CDK2CDK9 | |
| SCHEMBL2153112 | 0.78 | CDK2 (0.36) | CDK2CDK9ALDH1A1 | |
| SCHEMBL28597113 | 0.77 | TAS2R14 (0.44) | TAS2R14NAMPTNPC1S1PR2S1PR4 | |
| SCHEMBL119494 | 0.77 | CDK2 (0.39) | CDK2CDK9NAMPT | |
| SCHEMBL2153234 | 0.77 | CDK2 (0.36) | CDK2CDK9 | |
| SCHEMBL9610902 | 0.76 | CDK2 (0.37) | CDK2CDK9LMNANPSR1HTT | |
| SCHEMBL2745762 | 0.75 | CDK2 (0.46) | CDK2CDK9NPC1ALDH1A1RAB9A | |
| SCHEMBL14103878 | 0.75 | CDK2 (0.43) | CDK2CDK9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511149-B2 | Process for the oxidation of certain substituted sulfilimines to insecticidal sulfoximines | DOW AGROSCIENCES LLC (US) | 2009-03-31 | — | — | US | disclosed |
| US-7511149-B2 | Process for the oxidation of certain substituted sulfilimines to insecticidal sulfoximines | DOW AGROSCIENCES LLC (US) | 2009-03-31 | — | — | US | disclosed |
| WO-2008097235-A1 | PROCESS FOR THE OXIDATION OF CERTAIN SUBSTITUTED SULFILIMINES TO INSECTICIDAL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080194634-A1 | Process for the oxidation of certain substituted sulfilimines to insecticidal sulfoximines | CORTEVA AGRISCIENCE LLC | 2008-08-14 | — | — | US | disclosed |
| US-20080194634-A1 | Process for the oxidation of certain substituted sulfilimines to insecticidal sulfoximines | CORTEVA AGRISCIENCE LLC | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194634-A1 | Process for the oxidation of certain substituted sulfilimines to insecticidal sulfoximines | SMOX, TST, SPR | CDK2 4415/4885CDK9 3645/4885TAS2R14 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.