Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | NPC1 | O15118 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.64 |
| ▸ | RELA | Q04206 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650263 | 0.83 | NPC1 (0.89) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL3263307 | 0.83 | KDM4E (0.71) | ATAD2RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL16771498 | 0.82 | ATAD2 (1.00) | ATAD2RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL29454512 | 0.82 | ATAD2 (1.00) | ATAD2RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL7059841 | 0.80 | ALDH1A1 (0.73) | ATAD2RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL13762461 | 0.80 | KDM4E (0.70) | ATAD2RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL3248568 | 0.78 | ALDH1A1 (0.50) | ATAD2RAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL155874 | 0.78 | KCNH2 (0.50) | TP53KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL19844750 | 0.77 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL15453449 | 0.77 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | MONSANTO TECHNOLOGY LLC (US) | 2017-12-28 | — | — | US | disclosed |
| EP-2786993-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-01 | — | — | US | disclosed |
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-01 | — | — | US | disclosed |
| US-9642364-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2017-05-09 | — | — | US | disclosed |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-06-04 | — | — | US | disclosed |
| EP-2786992-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786993-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| EP-2786994-A1 | Compositions and methods for controlling nematodes | Monsanto Technology LLC (US) | 2014-10-08 | — | — | EP | disclosed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | disclosed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152247-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ATAD2 553/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | ATAD2 553/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ATAD2 553/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | ATAD2 510/4885RAB9A 3486/4885NPC1 3394/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ATAD2 553/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ATAD2 553/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20170367338-A1 | COMPOSITIONS AND METHODS FOR IMPROVING AGRONOMIC CHARACTERISTICS OF PLANTS | CYP51A1, MT-CO3, ACOX3 | ATAD2 204/4885RAB9A 3594/4885NPC1 3561/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | ATAD2 571/4885RAB9A 4578/4885NPC1 4073/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | ATAD2 553/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | ATAD2 553/4885RAB9A 3412/4885NPC1 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.