Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 10/20 | 0.33 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280018 | 0.89 | P2RX3 (0.38) | ABCB1ABCG2P2RX3IDH1 | |
| SCHEMBL4280686 | 0.88 | P2RX3 (0.34) | P2RX3IDH1KDM4EALDH1A1GFER | |
| SCHEMBL8285787 | 0.86 | KDM4E (0.37) | P2RX3IDH1KDM4EALDH1A1GFER | |
| SCHEMBL8285797 | 0.85 | ABCB1 (0.36) | ABCB1ABCG2P2RX3KDM4EALDH1A1 | |
| SCHEMBL8283679 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1GFER | |
| SCHEMBL14003034 | 0.80 | KDM4E (0.39) | KDM4EALDH1A1GFER | |
| SCHEMBL13932114 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1GFER | |
| SCHEMBL4284545 | 0.75 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL8284750 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1GFER | |
| SCHEMBL8284613 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | NQO2, NOX3, NOX1 | ABCB1 2788/4885ABCG2 1367/4885P2RX3 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.