Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.33 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280686 | 0.92 | P2RX3 (0.34) | KDM4EALDH1A1GFERP2RX3IDH1 | |
| SCHEMBL13932134 | 0.86 | ABCB1 (0.36) | KDM4EALDH1A1GFERP2RX3IDH1 | |
| SCHEMBL8285786 | 0.85 | KDM4E (0.37) | KDM4EALDH1A1GFERHPGDRAB9A | |
| SCHEMBL4280018 | 0.84 | P2RX3 (0.38) | P2RX3IDH1 | |
| SCHEMBL8283679 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1GFERHPGDRAB9A | |
| SCHEMBL14003034 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1GFERHPGDRAB9A | |
| SCHEMBL8284613 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1GFERHPGDRAB9A | |
| SCHEMBL13932114 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1GFERHPGDRAB9A | |
| SCHEMBL4284545 | 0.75 | KDM4E (0.37) | KDM4EALDH1A1HPGD | |
| SCHEMBL8284750 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1GFERHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | BONFANTI JEAN-FRANCOIS | 2009-02-05 | — | — | US | disclosed |
| WO-2005058870-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036466-A1 | AMINO-BENZIMIDAZOLES DERIVATIVES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | NQO2, NOX3, NOX1 | KDM4E 3254/4885ALDH1A1 2090/4885GFER 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.