Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10203389 | 0.89 | HDAC3 (0.52) | GABRA1GABRB2PTGER1PTGER4PTGER3 | |
| SCHEMBL10203390 | 0.86 | MAPT (0.54) | — | |
| SCHEMBL8083913 | 0.85 | ALDH1A1 (0.51) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL13544025 | 0.84 | KEAP1 (0.44) | KEAP1PTGER1PTGER4PTGER3PTGER2 | |
| Bicarbonate SCHEMBL27568192 | 0.84 | GABRA1 (0.58) | GABRA1GABRB2 | |
| SCHEMBL59198 | 0.84 | KEAP1 (0.65) | KEAP1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL27566829 | 0.84 | GABRA1 (0.46) | GABRA1GABRB2FFAR4ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL5685702 | 0.82 | GABRA1 (0.65) | GABRA1GABRB2 | |
| SCHEMBL3808149 | 0.81 | AKR1B1 (0.55) | GABRA1GABRB2KDM4E | |
| SCHEMBL3136623 | 0.81 | MTNR1A (0.45) | GABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620854-A | Chemically modified N-vinyl pyrrolidone, modification method thereof and polymer | 仲恺农业工程学院 | 2021-11-09 | — | — | CN | claimed |
| US-20180311186-A1 | PHARMACEUTICAL FORMULATION FOR BEDWETTING AND METHOD OF USE THEREOF | WELLESLEY PHARMACEUTICALS, LLC | 2018-11-01 | — | — | US | claimed |
| US-20180296676-A1 | PHARMACEUTICAL FORMULATION FOR REDUCING BLADDER SPASMS AND METHOD OF USE THEREOF | WELLESLEY PHARMACEUTICALS, LLC | 2018-10-18 | — | — | US | claimed |
| CN-106540052-A | A kind of Western medicine combination for treating flu and preparation method thereof | 郑州郑先医药科技有限公司 | 2017-03-29 | — | — | CN | claimed |
| EP-1898930-A2 | TREATMENT OF INFLAMMATORY CONDITIONS | Dynamis Therapeutics, Inc. (US) | 2008-03-19 | — | — | EP | claimed |
| US-20070066571-A1 | Novel bisphosphonates having anti-inflammatory and/or pain-killing properties | STOCKEL RICHARD F | 2007-03-22 | — | — | US | claimed |
| WO-2006138609-A2 | TREATMENT OF INFLAMMATORY CONDITIONS | DYNAMIS THERAPEUTICS, INC. (US) | 2006-12-28 | — | — | WO | claimed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| EP-0194693-B1 | POLYPRENYL COMPOUNDS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Eisai Co., Ltd. (JP) | 1989-07-26 | — | — | EP | claimed |
| US-3987094-A | PREPARING CARBOXYLIC ACIDS FROM GLYCIDONITRILES | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | claimed |
| JP-56097224-A | — | — | None | — | — | JP | disclosed |
| CN-113330304-B | Reduction of in vivo analyte signal degradation using multiple metals | 传感技术股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-112955250-B | Method and device for carrying out chemical reactions under elevated pressure | 巴斯夫欧洲公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117677383-A | Combinations of ketone bodies or ketone-forming compounds, analgesics or antioxidants | 瑞士凯托股份公司 | 2024-03-08 | — | — | CN | disclosed |
| US-11850578-B2 | Method and apparatus for performing a chemical reaction under elevated pressure | BASF SE (DE) | 2023-12-26 | — | — | US | disclosed |
| US-4391814-A | Derivatives of antiphlogistically effective carboxylic acids, their preparation and medicinal use | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-07-05 | — | — | US | disclosed |
| EP-0054812-A1 | Derivatives of antiphlogistically active carboxylic acids, their preparation and medical application | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-06-30 | — | — | EP | disclosed |
| JP-S5697224-A | ANTIPYRETIC ANALGESIC COMPOSITION | KAKEN PHARMACEUT CO LTD | 1981-08-05 | — | — | JP | disclosed |
| US-4107439-A | Process for preparing arylalkanoic acid derivatives | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| JP-S05697224-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066571-A1 | Novel bisphosphonates having anti-inflammatory and/or pain-killing properties | ENPP2, CD47, SOST | KEAP1 3858/4885GABRA1 884/4885GABRB2 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.