Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087384 | 0.86 | MAOB (0.53) | CYP3A4 | |
| SCHEMBL1396326 | 0.86 | RAB9A (0.46) | ALDH1A1KMT2APOLBSMN1; SMN2CYP3A4 | |
| SCHEMBL11142995 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KMT2AABCC1POLBSMN1; SMN2 | |
| SCHEMBL6426131 | 0.85 | MAPT (0.62) | ALDH1A1KMT2APOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL10790625 | 0.84 | LMNA (0.53) | ALDH1A1KMT2ASMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL1396267 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBSMN1; SMN2CYP3A4 | |
| P-Xylene SCHEMBL8521620 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KMT2APOLBSMN1; SMN2CYP3A4 | |
| SCHEMBL9357885 | 0.81 | CHRNB2 (0.61) | ALDH1A1KMT2AABCC1POLBSMN1; SMN2 | |
| SCHEMBL5096534 | 0.79 | MAOB (0.48) | ALDH1A1KMT2APOLBCYP3A4PPARA | |
| SCHEMBL23632078 | 0.79 | KMT2A (0.45) | ALDH1A1KMT2APOLBSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288612-B1 | GABAA RECEPTOR MODULATORS | GABATHER AB (SE) | 2015-07-29 | — | — | EP | disclosed |
| US-8809355-B2 | GABAA receptor modulators | INNOVATIONSPATENT SVERIGE AB (SE) | 2014-08-19 | — | — | US | disclosed |
| US-20110092525-A1 | GABAA RECEPTOR MODULATORS | GABATHER AB (SE) | 2011-04-21 | — | — | US | disclosed |
| EP-2288612-A1 | GABAA RECEPTOR MODULATORS | Forskarpatent i Syd AB (SE) | 2011-03-02 | — | — | EP | disclosed |
| WO-2009123537-A1 | GABAa RECEPTOR MODULATORS | FORSKARPATENT I SYD AB (SE) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092525-A1 | GABAA RECEPTOR MODULATORS | GABRA5, GABRA1, GABRA2 | ALDH1A1 716/4885KMT2A 1156/4885ABCC1 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.