SCHEMBL139734

SCHEMBL139734

CO[Si](OC)(OC)C(C)c1ccccc1C(C)[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
ESR1 P03372 1/20 0.34
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
ACHE P22303 1/20 0.32
TSHR P16473 2/20 0.32
CYP1A2 P05177 3/20 0.32
LMNA P02545 2/20 0.32
CYP3A4 P08684 2/20 0.32
HPGD P15428 2/20 0.32
BLM P54132 2/20 0.32
HIF1A Q16665 2/20 0.32
FAAH O00519 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
GABRB3 P28472 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27849377 0.89 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL19003107 0.87 ESR1 (0.48) ESR1ACHETSHRCYP1A2LMNA
SCHEMBL28330763 0.87 CA1 (0.48) CA1CA2ACHETSHRPTGS1
SCHEMBL1765958 0.85 GABRA1 (0.54) GABRA1GABRB2CA1CA2TSHR
SCHEMBL10772792 0.85 ALDH1A1 (0.39) GABRA1GABRB2CA1CA2ACHE
SCHEMBL6655792 0.85 ADRB2 (0.40) TSHRCYP1A2LMNACYP3A4HPGD
SCHEMBL15672877 0.82 ALDH1A1 (0.47) CYP1A2ALDH1A1CYP2C19CYP2C9
SCHEMBL28936286 0.82 MAPT (0.37) GABRA1GABRB2TSHRCYP3A4HPGD
SCHEMBL3679833 0.80 PNMT (0.35) IDO1
SCHEMBL2111676 0.80 IDO1 (0.35) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 869 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629657-B2 Lithium ion adsorbents EMPOWER INNOVATION & TECHNOLOGY LLC (US) 2026-05-19 US claimed
EP-4688684-A1 COATED LENS BODY Rodenstock GmbH (DE) 2026-02-11 EP claimed
US-12516263-B2 Compositions for reducing friction or stiction of a surface, methods and articles comprising the same ACTNANO, INC. (US) 2026-01-06 US claimed
EP-4665801-A1 COMPOSITIONS FOR REDUCING FRICTION OR STICTION OF A SURFACE, METHODS AND ARTICLES COMPRISING THE SAME Actnano, Inc. (US) 2025-12-24 EP claimed
CN-119799274-A Peroxide type primer for addition type liquid silica gel adhesive molding silica gel and preparation method thereof 深圳市康利邦科技有限公司 2025-04-11 CN claimed
EP-2262576-B1 COMPOSITE MATERIALS CONTAINING NANOPARTICLES AND THEIR USE IN CHROMATOGRAPHY WATERS TECHNOLOGIES CORP (US) 2025-03-12 EP claimed
WO-2024200260-A1 COATED LENS BODY RODENSTOCK GMBH (DE) 2024-10-03 WO claimed
WO-2024173535-A1 COMPOSITIONS FOR REDUCING FRICTION OR STICTION OF A SURFACE, METHODS AND ARTICLES COMPRISING THE SAME ACTNANO, INC. (US) 2024-08-22 WO claimed
US-20240279564-A1 COMPOSITIONS FOR REDUCING FRICTION OR STICTION OF A SURFACE, METHODS AND ARTICLES COMPRISING THE SAME ACTNANO, INC. 2024-08-22 US claimed
CN-118496675-A Elastic anti-corrosion silica gel sealing gasket and preparation method thereof 江苏中迪新材料技术有限公司 2024-08-16 CN claimed
US-20030215649-A1 First coating layer of a silane compound, a hydrolysis reaction product of the silane compound or a polymeric silane compound, or mixture (free of sulfide group), a second layer of a polymer and a photoactivable crosslinker SURMODICS, INC. 2003-11-20 US claimed
WO-2003081223-A2 SENSORS WITH VARIABLE RESPONSE BEHAVIOR HRL LABORATORIES, LLC (US) 2003-10-02 WO claimed
JP-2002543039-A 2002-12-17 JP claimed
WO-2002094410-A1 SOL-GEL DENDRON SEPARATION AND EXTRACTION CAPILLARY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-11-28 WO claimed
WO-2002072225-A1 HIGH EFFICIENCY SOL-GEL GAS CHROMATOGRAPHY COLUMN UNIVERSITY OF SOUTH FLORIDA (US) 2002-09-19 WO claimed
EP-1203032-A1 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2002-05-08 EP claimed
US-6326416-B1 MIXTURE OF RADIATION CURABLE OLIGOMER AND ADHESION PROMOTER CORNING INCORPORATED 2001-12-04 US claimed
US-6316516-B1 FOR PRODUCING PROTECTIVE COATINGS, FOR ENCAPSULATING OPTICAL FIBERS TO ENHANCE DURABILITY, NON-DELAMINATING CORNING INCORPORATED 2001-11-13 US claimed
WO-2000066636-A1 COATING COMPOSITION FOR OPTICAL FIBERS CORNING INCORPORATED (US) 2000-11-09 WO claimed
US-5622782-A USEFUL IN MANUFACTURE OF PRINTED CIRCUIT BOARDS GOULD INC. (US) 1997-04-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629657-B2 Lithium ion adsorbents ILK, SDC1, LAMTOR3 GABRA1 3101/4885GABRB2 3156/4885ESR1 2941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.