SCHEMBL3679833

SCHEMBL3679833

CO[Si](OC)(OC)C(C)c1ccccc1CN

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.35
TAAR1 Q96RJ0 3/20 0.34
DPP4 P27487 2/20 0.33
IDO1 P14902 2/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31
AOC1 P19801 1/20 0.30
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28936286 0.84 MAPT (0.37) OPRM1OPRD1OPRK1OPRL1
SCHEMBL2111676 0.82 IDO1 (0.35) IDO1
SCHEMBL29393805 0.82 NPBWR1 (0.33)
SCHEMBL139764 0.82 NPBWR1 (0.33)
SCHEMBL139734 0.80 GABRA1 (0.36) IDO1
SCHEMBL9480548 0.80 CHRM2 (0.45)
SCHEMBL1492149 0.79 ATM (0.35)
SCHEMBL10772792 0.76 ALDH1A1 (0.39) IDO1
SCHEMBL28350065 0.75 L3MBTL1 (0.37)
SCHEMBL394900 0.74 GABRA1 (0.44) PNMTTAAR1DPP4OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150185512-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-07-02 US disclosed
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2013-01-24 US disclosed
EP-1764118-B1 Polymer coating for medical devices GILEAD PALO ALTO INC (US) 2010-08-25 EP disclosed
EP-1937328-B1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS INC (US) 2009-08-26 EP disclosed
US-7419709-B2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2008-09-02 US disclosed
US-20080160166-A1 POLYMER COATING FOR MEDICAL DEVICES RYPACEK FRANTISEK 2008-07-03 US disclosed
EP-1937328-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2008-07-02 EP disclosed
US-7364768-B2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2008-04-29 US disclosed
WO-2007041972-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2007-04-19 WO disclosed
US-20070071926-A1 Polymer coating for medical devices RYPACEK FRANTISEK 2007-03-29 US disclosed
EP-1764118-A2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2007-03-21 EP disclosed
US-7160592-B2 Polymer coating for medical devices CV THERAPEUTICS, INC. (US) 2007-01-09 US disclosed
EP-1492581-B1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS INC (US) 2006-12-20 EP disclosed
US-20060093771-A1 Polymer coating for medical devices CV THERAPEUTICS, INC. 2006-05-04 US disclosed
EP-1492581-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2005-01-05 EP disclosed
US-20030219562-A1 Polymer coating for medical devices CV THERAPEUTICS, INC. 2003-11-27 US disclosed
WO-2003068289-A1 POLYMER COATING FOR MEDICAL DEVICES CV THERAPEUTICS, INC. (US) 2003-08-21 WO disclosed
EP-0980895-A1 HIGH-MOLECULAR ALIPHATIC POLYESTER RESIN COMPOSITION Showa Denko Kabushiki Kaisha (JP) 2000-02-23 EP disclosed
US-4863831-A Photosensitive lithographic plate requiring no dampening water having a gelatin primer layer FUJI PHOTO FILM CO., LTD. (JP) 1989-09-05 US disclosed
US-4861698-A HARDENED GELATIN, SILICONE RUBBER FUJI PHOTO FILM CO., LTD. (JP) 1989-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130021546-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND SUBSTRATE USED IN SAME ZKSCAN2, L1CAM, SDC2 PNMT 4344/4885TAAR1 3101/4885DPP4 3210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.