Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000124 | 0.83 | MAOA (0.39) | MAOAMAOBSCN3APKMMEN1 | |
| SCHEMBL13999724 | 0.80 | MAOA (0.39) | MAOAMAOBPKM | |
| SCHEMBL11273478 | 0.74 | DRD2 (0.46) | SCN3ADRD2HTR2AHTR2BNLRP3 | |
| SCHEMBL11660041 | 0.73 | TRPA1 (0.43) | SCN3ADRD2NLRP3CYP2C9MEN1 | |
| SCHEMBL1842965 | 0.72 | HDAC3 (0.44) | SCN3ADRD2HTR2AHTR2BNLRP3 | |
| SCHEMBL19036558 | 0.72 | MAPT (0.47) | MAOAMAOBDRD2HDAC3HDAC1 | |
| SCHEMBL13999721 | 0.71 | ALDH1A1 (0.49) | PKMMEN1KMT2A | |
| SCHEMBL814598 | 0.70 | MAPT (0.48) | SCN3ACYP2C9MEN1CYP1A2NFKB1 | |
| SCHEMBL28921103 | 0.69 | ALDH1A1 (0.49) | DRD2HTR2AHTR2BNLRP3PKM | |
| SCHEMBL11656144 | 0.69 | ACHE (0.44) | SCN3ANLRP3CYP2C9MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |