Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999720 | 0.80 | MAOA (0.39) | MAOAMAOBPKM | |
| SCHEMBL14000124 | 0.77 | MAOA (0.39) | MAOAMAOBPTGER2ALDH1A1MAPT | |
| SCHEMBL13999721 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTPKM | |
| SCHEMBL18488826 | 0.69 | RAPGEF4 (0.44) | RAPGEF4PTGER2 | |
| SCHEMBL14431745 | 0.68 | PKM (0.41) | MAOAMAOBALDH1A1PKM | |
| SCHEMBL14000133 | 0.68 | GUCY1A1 (0.51) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL18490818 | 0.67 | RAPGEF4 (0.42) | RAPGEF4PTGER2 | |
| SCHEMBL14000123 | 0.66 | GAA (0.49) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5233047 | 0.66 | MAOA (0.61) | MAOAMAOBALDH1A1 | |
| SCHEMBL19036558 | 0.65 | MAPT (0.47) | MAOAMAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |