Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 6/20 | 0.39 |
| ▸ | MPO | P05164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836246 | 0.81 | MKNK2 (0.42) | MPOMAPTSMN1; SMN2FLT3JAK2 | |
| SCHEMBL13999721 | 0.72 | ALDH1A1 (0.49) | MAPTPKMALDH1A1 | |
| SCHEMBL14495394 | 0.70 | P2RX7 (0.47) | ICMTMPOSLC6A4 | |
| SCHEMBL28037697 | 0.69 | CA3 (0.45) | ICMTMPOMAPTMAPK8SLC6A4 | |
| SCHEMBL1115269 | 0.69 | MAPK8 (0.52) | ICMTMPOMAPK8SLC6A4 | |
| SCHEMBL30148003 | 0.69 | MAPK8 (0.52) | ICMTMPOMAPK8SLC6A4 | |
| Hydrochloric Acid SCHEMBL8894497 | 0.68 | IDO1 (0.52) | ICMTMPOMAPK8SLC6A4 | |
| SCHEMBL28148702 | 0.67 | ICMT (0.47) | ICMTMPOMAPK8SLC6A4 | |
| SCHEMBL1345638 | 0.66 | P2RX7 (0.45) | ICMTMPOPKMMAPK8SLC6A4 | |
| SCHEMBL1395757 | 0.66 | ALDH1A1 (0.44) | ICMTMPOMAPTSLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110885328-B | Sulfonamide compounds as sodium channel blockers and uses thereof | 成都康弘药业集团股份有限公司 | 2022-08-12 | — | — | CN | disclosed |