Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9402845 | 0.77 | TSHR (0.42) | LMNACYP2C19 | |
| SCHEMBL19728841 | 0.74 | LMNA (0.37) | LMNACYP2C19FDPS | |
| SCHEMBL9885852 | 0.74 | CA2 (0.32) | FDPS | |
| SCHEMBL11367504 | 0.72 | FDPS (0.46) | FDPS | |
| SCHEMBL9063893 | 0.69 | CYP2C19 (0.33) | LMNACYP2C19 | |
| SCHEMBL14248304 | 0.67 | LMNA (0.33) | LMNACYP2C19 | |
| SCHEMBL14550537 | 0.67 | GABBR2 (0.34) | LMNACYP2C19FDPS | |
| SCHEMBL5897537 | 0.67 | FDPS (0.41) | LMNACYP2C19FDPS | |
| SCHEMBL14796398 | 0.67 | LMNA (0.37) | LMNACYP2C19 | |
| SCHEMBL10784498 | 0.65 | LMNA (0.43) | LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | TARGANTA THERAPEUTICA INC. (CA) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | BPGM, PSPH, PGLS | LMNA 3228/4885CYP2C19 2955/4885FDPS 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.