Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMD1 | P17707 | 8/20 | 0.55 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.51 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704527 | 0.87 | NADK (0.57) | HSPA5HSPA8RXFP1HSD17B10ADORA3 | |
| SCHEMBL3701954 | 0.87 | NADK (0.57) | HSPA5HSPA8RXFP1HSD17B10ADORA3 | |
| SCHEMBL19680323 | 0.87 | AHCY (0.55) | HSPA5HSPA8RXFP1HSD17B10GAPDH | |
| SCHEMBL8621042 | 0.87 | AMD1 (0.52) | AMD1HSPA5HSPA8RXFP1HSD17B10 | |
| SCHEMBL8621046 | 0.87 | AMD1 (0.52) | AMD1HSPA5HSPA8RXFP1HSD17B10 | |
| SCHEMBL29328694 | 0.87 | HSPA8 (0.48) | AMD1HSPA5HSPA8RXFP1HSD17B10 | |
| SCHEMBL2582785 | 0.86 | HSPA5 (0.47) | AMD1HSPA5HSPA8RXFP1HSD17B10 | |
| SCHEMBL19121006 | 0.81 | ADORA3 (0.64) | AMD1HSPA5HSPA8RXFP1HSD17B10 | |
| SCHEMBL13479946 | 0.81 | ADORA3 (0.64) | AMD1HSPA5HSPA8RXFP1HSD17B10 | |
| SCHEMBL14544481 | 0.79 | HSPA8 (0.60) | AMD1HSPA5HSPA8RXFP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293665-A1 | Purine Nucleotide Derivatives | LAURAS AS (NO) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293665-A1 | Purine Nucleotide Derivatives | CGAS, PDE8A, PDE7A | AMD1 820/4885HSPA5 3164/4885HSPA8 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.